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Volume 7, Number 2—April 2001
THEME ISSUE
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections
Introduction

The Impact of Hospital-Acquired Bloodstream Infections

Richard P. WenzelComments to Author  and Michael B. Edmond
Author affiliations: Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA

Main Article

Table 1

Deaths and death rates in the United States, 1997 (1)

No. of deaths Crude death rate
Cause of death (thousands) (per 100,000) % of all deaths
Heart disease 725.8 271.2 31.4
Malignancies 537.4 200.8 23.2
Cerebrovascular disease 159.9 59.7 6.9
Pneumonia and influenza 88.4 33.0 3.8
Septicemia 22.6 8.4 0.97

Main Article

References
  1. National Center for Health Statistics. Vital statistics of the United States. 119th ed. Washington: U.S. Census Bureau. Statistical abstract of the United States;1999. p.99.
  2. Wenzel  RP. The mortality of hospital-acquired bloodstream infections: need for a new vital statistic? Int J Epidemiol. 1988;17:2257. DOIPubMed
  3. Broderick  A, Mori  M, Nettleman  MD, Streed  SA, Wenzel  RP. Nosocomial infections: validation of surveillance and computer modeling to identify patients at risk. Am J Epidemiol. 1990;131:73442.PubMed
  4. Morrison  AJ Jr, Kaiser  DL, Wenzel  RP. A measurement of the efficacy of nosocomial infection control using the 95 percent confidence interval for infection rates. Am J Epidemiol. 1987;126:2927.PubMed
  5. Wenzel  RP, Osterman  CA, Townsend  TR, Veazey  JM Jr, Servis  KH, Miller  LS, Development of a statewide program for surveillance and reporting of hospital-acquired infections. J Infect Dis. 1979;140:7416. DOIPubMed
  6. Pittet  D, Wenzel  RP. Nosocomial bloodstream infection: secular trends in rates and mortality in a tertiary health care center. Arch Intern Med. 1995;155:117784. DOIPubMed
  7. Edmond  MB, Wallace  SE, McClish  DK, Pfaller  MA, Jones  RN, Wenzel  RP. Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis. 1999;29:23944. DOIPubMed
  8. Wenzel  RP. Attributable mortality: the promise of better antimicrobial therapy. J Infect Dis. 1998;178:9179. DOIPubMed
  9. Haley  RW, Culver  DH, White  JW, Morgan  WM, Emori  TG, Munn  VP, The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol. 1985;121:182205.PubMed
  10. Wenzel  RP. The economics of nosocomial infection. J Hosp Infect. 1995;31:7987. DOIPubMed
  11. Darouiche  RO, Raad  II, Heard  SO, Thornby  JI, Wenker  OC, Gabrielli  A, A comparison of two antimicrobial-impregnated central venous catheters. N Engl J Med. 1999;340:18. DOIPubMed
  12. Wenzel  RP, Edmond  MB. The evolving technology of venous access. N Engl J Med. 1999;340:489. DOIPubMed
  13. Bischoff  WE, Reynolds  TM, Sessler  CN, Edmond  MB, Wenzel  RP. Handwashing compliance by health care workers: the impact of introducing an accessible, alcohol-based hand disinfectant. Arch Intern Med. 2000;160:101721. DOIPubMed
  14. Doebbeling  BN, Stanley  GL, Sheetz  CT, Pfaller  MA, Houston  AK, Annis  L, Comparative efficacy of alternative handwashing agents in reducing nosocomial infections in intensive care units. N Engl J Med. 1992;327:8893. DOIPubMed

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Page created: May 10, 2011
Page updated: May 10, 2011
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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