Volume 7, Number 4—August 2001
THEME ISSUE
West Nile Virus
West Nile Virus
West Nile Virus Infection in the Golden Hamster (Mesocricetus auratus): A Model for West Nile Encephalitis
Shu-Yuan Xiao, Hilda Guzman, Hui Zhang, Amelia P.A. Travassos da Rosa, and Robert B. Tesh
Table 2
Viremia and hemagglutination inhibition (HI) antibody response in 10 adult hamsters following intraperitoneal inoculation of 104 TCID50a of West Nile virus strain 385-99
| Animal no. | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 |
|---|---|---|---|---|---|---|---|
| 8001 | 4.3 (N)b | 5.0 (N) | 5.0 (N) | 3.3 (N) | 1.0 (80) | 1.0 (320) | <0.7 (640) |
| 8002 | 4.7 (N) | 5.5 (N) | 5.2 (N) | 3.5 (N) | 2.0 (80) | <0.7 (320) | <0.7 (640) |
| 8003 | 5.3 (N) | 5.3 (N) | 5.0 (N) | 3.5 (N) | 2.5 (40) | <0.7 (320) | <0.7 (NT) |
| 8004 | 2.0 (N) | 5.0 (N) | 5.0 (N) | 4.3 (N) | 2.5 (40) | 1.0 (160) | <0.7 (640) |
| 8005 | 4.0 (N) | 5.0 (N) | 5.5 (N) | 3.7 (N) | 1.7 (80) | 1.0 (320) | <0.7 (1280) |
| 8006 | 4.6 (N) | 5.2 (N) | 5.7 (N) | 4.3 (N) | 2.7 (80) | <0.7 (320) | <0.7 (2560) |
| 8007 | 4.3 (N) | 5.7 (N) | 4.6 (N) | 4.0 (N) | 2.0 (80) | 1.0 (320) | <0.7 (2560) |
| 8008 | 4.2 (N) | 5.8 (N) | 4.8 (N) | 1.8 (N) | 2.0 (80) | <0.7 (320) | <0.7 (640) |
| 8009 | 5.2 (N) | 5.2 (N) | 5.0 (N) | 3.2 (N) | 2.8 (80) | <0.7 (320) | <0.7 (1280) |
| 8010 | 4.7 (N) | 4.7 (N) | 5.5 (N) | 3.5 (N) | 1.8 (80) | 0.7 (320) | <0.7 (1280) |
aTCID50 = tissue culture infectious dose50
bLevel of viremia expressed as log10 TCID50 of virus/mL of blood. (reciprocal of HI antibody titer) N = < 1:20.
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