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Volume 7, Number 5—October 2001
Research

Intraoperative Redosing of Cefazolin and Risk for Surgical Site Infection in Cardiac Surgery

Giorgio Zanetti*†Comments to Author , Richard Giardina*, and Richard Platt*‡
Author affiliations: *Brigham and Women's Hospital, Harvard Medical School, and the CDC Eastern Massachusetts Prevention Epicenter, Boston, Massachusetts, USA; †University Hospital, Lausanne, Switzerland; ‡Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA

Main Article

Figure

Effect of intraoperative redosing of cefazolin on the probability of surgical site infection. Box-and-whisker plots represent the probabilities of surgical site infection in 1,548 patients undergoing cardiac surgery, stratified by procedure duration, with or without intraoperative redosing of cefazolin. The probabilities for each member of the cohort were computed on the basis of redosing of antibiotic prophylaxis, the patient's age, and the type and duration of the procedure. The mean is repres

Figure. . Effect of intraoperative redosing of cefazolin on the probability of surgical site infection. Box-and-whisker plots represent the probabilities of surgical site infection in 1,548 patients undergoing cardiac surgery, stratified by procedure duration, with or without intraoperative redosing of cefazolin. The probabilities for each member of the cohort were computed on the basis of redosing of antibiotic prophylaxis, the patient's age, and the type and duration of the procedure. The mean is represented by a triangle and the median by a bar within the boxes. There is no bar for procedures >400 min in duration because all the probabilities were clustered at the extremities of the boxes.

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