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Volume 7, Number 5—October 2001
Research

Intraoperative Redosing of Cefazolin and Risk for Surgical Site Infection in Cardiac Surgery

Giorgio Zanetti*†Comments to Author , Richard Giardina*, and Richard Platt*‡
Author affiliations: *Brigham and Women's Hospital, Harvard Medical School, and the CDC Eastern Massachusetts Prevention Epicenter, Boston, Massachusetts, USA; †University Hospital, Lausanne, Switzerland; ‡Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA

Main Article

Table 2

Independent predictors of surgical site infections after cardiac surgery

Predictor Adjusted odds ratio for SSIa 95% confidence interval pb
Procedures lasting <400 min
Agec 1.2 1.00-1.45 0.049
CABG surgery 1.84 1.05-3.20 0.032
Duration of surgeryd 1.38 1.00-1.82 0.032
Intraoperative redosing of antibiotics 1.27 0.80-2.02 0.319
Procedures lasting >400 min
CABG surgery 2.2 1.05-4.61 0.036
Intraoperative redosing of antibiotics 0.44 0.23-0.86 0.016

aSSI: surgical site infection; CABG: coronary artery bypass graft.
bWald test.
cOdds ratio for every additional decade of age.
dOdds ratio for every additional hour of surgery.

Main Article

Page created: April 26, 2012
Page updated: April 26, 2012
Page reviewed: April 26, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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