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Volume 8, Number 11—November 2002


Rifampin- and Multidrug-Resistant Tuberculosis in Russian Civilians and Prison Inmates: Dominance of the Beijing Strain Family

Francis Drobniewski*Comments to Author , Yanina Balabanova*, Michael Ruddy*, Laura Weldon*, Katya Jeltkova†, Timothy Brown*, Nadezdna Malomanova‡, Elvira Elizarova‡, Alexander Melentyey§, Ebgeny Mutovkin§, Svetlana Zhakharova‡, and Ivan Fedorin‡
Author affiliations: *Guy's King's and St Thomas' Medical School, King's College Hospital, London, United Kingdom; †Central Tuberculosis Research Institute, Moscow, Russian Federation; ‡Samara Oblast Dispensary, Samara City, Russian Federation; §Samara Prison TB Service, Samara City, Russian Federation;

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Table 1

Molecular resistance to rifampin and isoniazid in Mycobacterium tuberculosis isolates with proportional analysis by center/laboratory, Samara Oblast, Russian Federation

Laboratory location No. of isolates examined for rifampin resistance (n=130)a No. of rifampin-resistant isolates (%) No. of isoniazid-resistant isolates (%)b
All 134 78 (58.2) 66 (–)
Prison TB colony 45 36 (80.0) 27 (60.0)
City dispensary 1 11 4 (36.4) 4 (36.4)
City hospital 1 34 18 (52.9) 14 (41.2)
Novokubshev town laboratory 21 9 (42.9) 11 (52.4)
Oblast regional TB laboratory 19 11 (57.9) 10 (52.6)

aOf 140 cultures, 134 results were produced, but only 130 were available for results by center; 2 were M. gordonae, amplification failed for 4 cultures, and center could not be definitively identified for 4.
bOf 140 cultures, amplification products that could be evaluated were obtained from 128 cultures.

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