Volume 9, Number 10—October 2003
Dispatch
Wild-type Measles Virus in Brain Tissue of Children with Subacute Sclerosing Panencephalitis, Argentina
Table
Clinical, epidemiologic, and laboratory findings for eight pediatric subacute sclerosing panencephalitis (SSPE) patientsa
Patient | SSPE1 | SSPE2 | SSPE3 | SSPE4 | SSPE5 | SSPE6 | SSPE7 | SSPE8 |
---|---|---|---|---|---|---|---|---|
Date of birth | Jan-98 | Feb-98 | Jul-98 | Mar-98 | Nov-97 | Nov-97 | Sep-96 | Nov-97 |
Date of measles disease | Sep-98 | Sep-98 | May-99 | Sep-98 | Sep-98 | N/A | Jul-97 | Jul-98 |
Date of SSPE onset | May-01 | Dec-01 | Feb-02 | Jun-02 | Aug-02 | Sep-02 | Jan-03 | Feb-03 |
Geographic location | GBA | GBA | NW | GBA | GBA | GBA | NE | GBA |
CSF antibody titers | 1:1600 | 1:1600 | 1:3200 | 1:3200 | 1:400 | 1:400 | 1:1600 | 1:400 |
Serum antibody titers | >1:3200 | >1:3200 | 1:12800 | >1:3200 | >1:3200 | 1:12800 | N/A | 1:400 |
Initial diagnosis | Progressive myoclonic epilepsy | Acute disseminated encephalo-myelitis | Progressive myoclonic epilepsy | Neuronal ceroid lipofucsinosis | Lennox Gastaut syndrome | Progressive myoclonic atonic epilepsy | Chorioretinitis | Ataxia |
aMolecular studies were done for SSPE patients highlighted in bold type. N/A, not available; GBA, greater Buenos Aires metropolitan area; NW, northwestern region from Argentina; NE, northeastern region from Argentina; CSF, cerebrospinal fluid.