Table 1

Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family

Mina Ebrahimi Rad*, Pablo Bifani†, Carlos Martin‡, Kristin Kremer§, Sofia Samper‡, Jean Rauzier*, Barry N. Kreiswirth¶, Jesus Blazquez#, Marc Jouan*, Dick van Soolingen§, and Brigitte Gicquel*

Author affiliations: *Institut Pasteur, Paris, France; †Institut Pasteur, Lille, France; ‡Universidad de Zaragoza, Zaragoza, Spain; §National Institute of Public Health and the Environment, Bilthoven, the Netherlands; ¶Public Health Research Institute, Newark, New Jersey, USA; #National Institute of Health, Madrid, Spain

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Characteristics of Mycobacterium tuberculosis complex strains originating from 35 different countries^a

Strains	Genotype	No. isolates	Country of isolation	Group	mutT2	mutT4	ogt
ZA20/65	W-Beijing	2	Spain	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
ZA67-69	W-Beijing	3	Spain	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
ZA11/16	Haarlem	2	Spain	2	wt	wt	Thr ACC 15 Ser AGC
ZA12-14/17	other	4	Spain	nd	wt	wt	wt
ZA19	M. bovis	1	Spain		wt	wt	wt
ZA15	other	1	Spain	nd	wt	wt	wt
ZA60-62	W-Beijing	3	Spain	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
CDC1551		1	USA	2	wt	wt	wt
H37Rv		1	USA	3	wt	wt	wt
MT210	W-Beijing	1	USA	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
20	W-Beijing	1	Mongolia	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
30	W-Beijing	1	South Africa	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
34	W-Beijing	1	Malaysia	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
43	W-Beijing	1	China	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
44	W-Beijing	1	Thailand	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
45	W-Beijing	1	Malaysia	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
91/102-6	W-Beijing	6	Vietnam	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
110/116/119/124-5/140-2	W-Beijing	8	the Netherlands	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
133	W-Beijing	1	South Africa	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
W4/10/126/129	W-Beijing	4	USA	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
W99	W-Beijing	1	Singapore	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
W147	W-Beijing	1	Russia	1	Gly GGA 58 CGA Arg	Arg CGG 48 GGG Gly	Gly GGG 12 Gly GGA
94	W-Beijing	1	Vietnam	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
111	W-Beijing	1	South Korea	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
115	W-Beijing	1	the Netherlands	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
5107(HG1)	W-Beijing	1	USA	1	wt	Arg CGG 48 GGG Gly	Arg CGC 37 Leu CTC
114, 139	W-Beijing	1	the Netherlands	1	wt	Arg CGG 48 GGG Gly	wt
166(HD6)	W-Beijing	1	USA	1	wt	Arg CGG 48 GGG Gly	wt
165(001)	W-Beijing	1	USA	1	wt	wt	Arg CGC 37 Leu CTC
107(LB)	W-Beijing	1	USA	1	wt	wt	wt
113	W-Beijing	1	the Netherlands	1	wt	wt	wt
122(CI1)	W-Beijing	1	USA	1	wt	wt	wt
IK/KY/LB2/DV/DU2/HI	W-Beijing	6	Russia	1	wt	wt	wt
N16	W-Beijing	1	USA	1	wt	wt	wt
AM	W-Beijing	1	USA	1	wt	wt	wt

^awt, wild-type alleles (identical to H37Rv strain); nd, not determined.

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Page created: December 22, 2010

Page updated: December 22, 2010

Page reviewed: December 22, 2010

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