Volume 10, Number 7—July 2004
Dispatch
Human Metapneumovirus and Severity of Respiratory Syncytial Virus Disease
Isaac Lazar*, Carla Weibel*, James Dziura*, David Ferguson*, Marie L. Landry*, and Jeffrey S. Kahn*
Table
Comparison between the group of children admitted to PICU with severe RSV disease and the group of children with mild RSV disease
| Characteristic | PICUa | Non PICUa | Statistical comparison (p value)b |
|---|---|---|---|
| Median age (range) |
7 wk (2 wk–21 mo) |
54 wk (10 d–4 y) |
0.025b |
| Prematurity (%) |
5/23 (21.7) |
3/23 (13.0) |
> 0.1c |
| RSVd PCR/DFAe (%) |
21/23 (91.3) |
23/23 (100) |
0.244c |
| Hospitalized (%) |
23/23 (100) |
8/23 (34.8) |
0.004c |
| Median CSSf (range) |
5 (3–6) |
1 (0–4) |
< 0.001b |
| PPVg (%) |
17/23 (73.9) |
0/23 (0) |
NDh |
| RSV/HMPVi co-infection | 0/23 (0) | 0/23 (0) | 1.0 |
aPICU, Pediatric Intensive Care Unit.
cWilcoxon rank sum test.
bχ2 test.
dRSV, respiratory syncytial virus.
eDFA, direct fluorescent antibody screen.
fCCS, clinical severity score.
gPPV, positive pressure ventilation.
hND, non-comparable as patients requiring PPV are admitted to the PICU.
iHMPV, human metapneumovirus.
Page created: January 27, 2011
Page updated: January 27, 2011
Page reviewed: January 27, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.