Volume 13, Number 6—June 2007
Research
Molecular Characteristics and Epidemiology of Meningococcal Carriage, Burkina Faso, 2003
Table 5
Sequence type (ST) | Phenotype | Place and time of meningococcal disease cases |
---|---|---|
ST-11 | W135:2a:P1.5,2 | Sporadic in Cameroon, Senegal, Burkina Faso, Central African Republic, Chad, Niger, and Ghana since 2003. Epidemic and major seasonal agent in Burkina Faso during 2002–2004 (including Bobo-Dioulasso) |
W135:NT:P1.5,2 | Sporadic in Bobo-Dioulasso, 2004 | |
W135:2a:P1.2, W135:NT:P1.2 | Sporadic in Niger, 2003 | |
Y:14:P1.5,2 | Sporadic in Bobo-Dioulasso, 2004 | |
ST-1966 (ST-11 complex) | W135:2a:P1.5,2 | Sporadic in Burkina Faso |
ST-2881 | W135:NT:P1.5,2 | Sporadic in Benin since 2003. Major seasonal agent in Niger during 2003 |
ST-5 | A:4:P1.9, A:21:P1.9 | Major seasonal agent in Niger, Senegal, and Burkina Faso during 2000–2001 |
ST-7 (ST-5 complex) | A:4:P1.9, A:21:P1.9 | Major seasonal agent and epidemic in Cameroon, Chad, Niger, Senegal, Benin, Burkina Faso, Ethiopia, and Nigeria |
ST-2859 (ST-5 complex) | A:4:P1.9, A:21:P1.9 | Major seasonal agent and epidemic in Burkina Faso since 2003 (including Bobo-Dioulasso) |
ST-751 | X:NT:P1.5, X:NT:P1.5,2 | Sporadic in Burkina Faso (including Bobo-Dioulasso), Niger, and Ghana |
ST-181 | X:NT:P1.5 | Sporadic in Niger |
ST-2880 | Y:14:P1.5,2 | Sporadic in Niger |
ST-4375 (ST-23 complex) | Polyagglutinable:14:P1.5,2 | Sporadic in Bobo-Dioulasso, 2004 |
W135:NT:P1.5,2 | Sporadic in Bobo-Dioulasso, 2004 | |
ST-23 (ST-23 complex) | Y:14:NST | Sporadic in Senegal |
ST-32, ST-2496 (ST-32 complex), ST-291 (ST-41/44 complex) | C:4:P1.16, B:4:P1.16, B:4:P1.7,16, B:4:P1.9 | Sporadic in Cameroon |
ST-192 |
NG:NT:NST |
Sporadic in Bobo-Dioulasso, 2003 and 2004 |
*Data were obtained from references 1,5,16,17,20–22, and the Neisseria multilocus sequencing typing website (http://pubmlst.org/ neisseria). |
References
- Nicolas P, Norheim G, Garnotel E, Djibo S, Caugant DA. Molecular epidemiology of Neisseria meningitidis isolated in the African meningitis belt between 1988 and 2003 shows dominance of sequence type 5 (ST-5) and ST-11 complexes. J Clin Microbiol. 2005;43:5129–35. DOIPubMedGoogle Scholar
- Kwara A, Adegbola RA, Corrah PT, Weber M, Achtman M, Morelli G, Meningitis caused by a serogroup W135 clone of the ET-37 complex of Neisseria meningitidis in West Africa. Trop Med Int Health. 1998;3:742–6.PubMedGoogle Scholar
- Taha MK, Parent du Chatelet I, Schlumberger M, Sanou I, Djibo S, de Chabalier F, Neisseria meningitidis serogroups S135 and A were equally prevalent among meningitis cases occurring at the end of 2001 epidemics in Burkina Faso and Niger. J Clin Microbiol. 2002;40:1083–4. DOIPubMedGoogle Scholar
- World Health Organization. Meningococcal disease, serogroup W135, Burkina Faso. Wkly Epidemiol Rec. 2002;77:152–5.PubMedGoogle Scholar
- Traoré Y, Njanpop-Lafourcade BM, Adjogble KLS, Lourd M, Yaro S, Nacro B, The rise and fall of epidemic Neisseria meningitidis serogroup W135 meningitis in Burkina Faso, 2002–5. Clin Infect Dis. 2006;43:817–22. DOIPubMedGoogle Scholar
- World Health Organization. Meningococcal disease, African meningitis belt, epidemic season 2006. Wkly Epidemiol Rec. 2006;81:119–20.PubMedGoogle Scholar
- Mueller JE, Yaro S, Traoré Y, Sangaré L, Tarnagda Z, Njanpop-Lafourcade BM, Neisseria meningitidis: carriage and immunity in Burkina Faso, 2003. J Infect Dis. 2006;193:812–20. DOIPubMedGoogle Scholar
- World Health Organization. Laboratory methods for the diagnosis of meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae: WHO communicable disease surveillance and response. WHO/CDS/CSR/EDC/99.7. Geneva: The Organization; 1999.
- Taha MK. Simultaneous approach for nonculture PCR-based identification and serogroup prediction of Neisseria meningitidis. J Clin Microbiol. 2000;38:855–7.PubMedGoogle Scholar
- Deghmane AE, Giogini D, Larribe M, Alonso JM, Taha MK. Down regulation of pili and capsule of Neisseria meningitidis upon contact with epithelial cells is mediated by crgA regulatory protein. Mol Microbiol. 2002;43:1555–64. DOIPubMedGoogle Scholar
- Poolman JT, Abdillahi H. Outer membrane protein serosubtyping of Neisseria meningitidis. Eur J Clin Microbiol Infect Dis. 1988;7:291–2. DOIPubMedGoogle Scholar
- Nicolas P, Parzy D, Martet G. Pulsed-field gel electrophoresis analysis of clonal relationships among Neisseria meningitidis A strains from different outbreaks. Eur J Clin Microbiol Infect Dis. 1997;16:541–4. DOIPubMedGoogle Scholar
- Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233–9.PubMedGoogle Scholar
- Maiden MC, Bygraves JA, Feil E, Morelli G, Russell JE, Urwin R, Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A. 1998;95:3140–5. DOIPubMedGoogle Scholar
- de Wals P, Bouckaert A. Methods for estimating the duration of bacterial carriage. Int J Epidemiol. 1985;14:628–34. DOIPubMedGoogle Scholar
- Nicolas P, Djibo S, Moussa A, Tenebray B, Boisier P, Chanteau S. Molecular epidemiology of meningococci isolated in Niger in 2003 shows serogroup A sequence type (ST)-7 and serogroup W135 ST-11 or ST-2881 strains. J Clin Microbiol. 2005;43:1437–8. DOIPubMedGoogle Scholar
- Parent du Châtelet I, Traore Y, Gessner BD, Antignac A, Naccro B, Njanpop-Lafourcade BM, Bacterial meningitis in Burkina Faso: surveillance using field-based polymerase chain reaction testing. Clin Infect Dis. 2005;40:17–25. DOIPubMedGoogle Scholar
- Amadou Hamidou A, Djibo S, Elhaj Mahamane A, Moussa A, Findlow H, Sidikou F, Prospective survey on carriage of Neisseria meningitidis and protective immunity to meningococci in schoolchildren in Niamey (Niger): focus on serogroup W135. Microbes Infect. 2006;8:2098–104. DOIPubMedGoogle Scholar
- Balmer P, Borrow R, Miller E. Impact of meningococcal C conjugate vaccine in the UK. J Med Microbiol. 2002;51:717–22.PubMedGoogle Scholar
- Forgor AA, Leimkugel J, Hodgson A, Bugri A, Dangy JP, Gagneux S, Emergence of W135 meningococcal meningitis in Ghana. Trop Med Int Health. 2005;10:1229–34. DOIPubMedGoogle Scholar
- Njanpop-Lafourcade BM, Parent du Chatelet I, Sanou O, Alonso JM, Taha MK. The establishment of Neisseria meningitidis serogroup W135 of the clonal complex ET-37/ST-11 as an epidemic clone and the persistence of serogroup A isolates. Microbes Infect. 2005;7:645–9.PubMedGoogle Scholar
- Ouedraogo-Traoré R, Høiby EA, Sanou I, Sangare L, Kyelem N, Ye-Ouattara D, Molecular characteristics of Neisseria meningitidis strains isolated in Burkina Faso in 2001. Scand J Infect Dis. 2002;34:804–7. DOIPubMedGoogle Scholar
- Swartley JS, Marfin AA, Edupuganti S, Liu LJ, Cieslak P, Perkins B, Capsule switching of Neisseria meningitidis. Proc Natl Acad Sci U S A. 1997;94:271–6. DOIPubMedGoogle Scholar
- Raghunathan PL, Jones JD, Tiendrebeogo SR, Sanou I, Sangaré L, Kouanda S, Predictors of immunity after a major serogroup W-135 meningococcal disease epidemic, Burkina Faso, 2002. J Infect Dis. 2006;193:607–16. DOIPubMedGoogle Scholar
- Blakebrough IS, Greenwood BM, Whittle HC, Bradley AK, Gilles HM. The epidemiology of infections due to Neisseria meningitidis and Neisseria lactamica in a northern Nigerian community. J Infect Dis. 1982;146:626–37.PubMedGoogle Scholar
- Gagneux SP, Hodgson A, Smith TA, Wirth T, Erhard I, Morelli G, Prospective study of a serogroup X Neisseria meningitidis outbreak in northern Ghana. J Infect Dis. 2002;185:618–26. DOIPubMedGoogle Scholar
- Taha MK, Giorgini D, Ducos-Galand M, Alonso JM. Continuing diversification of Neisseria meningitidis W135 as a primary cause of meningococcal disease after emergence of the serogroup in 2000. J Clin Microbiol. 2004;42:4158–63. DOIPubMedGoogle Scholar
- Yazdankhah SP, Kriz P, Tzanakaki G, Kremastinou J, Kalmusova J, Musilek M, Distribution of serogroups and genotypes among disease-associated and carried isolates of Neisseria meningitidis from the Czech Republic, Greece, and Norway. J Clin Microbiol. 2004;42:5146–53. DOIPubMedGoogle Scholar
- Maiden MC, Stuart JM; UK Meningococcal Carriage Group. Carriage of serogroup C meningococci 1 year after meningococcal C conjugate polysaccharide vaccination. Lancet. 2002;359:1829–31. DOIPubMedGoogle Scholar
- Ala’Aldeen DA, Neal KR, Ait-Tahar K, Nguyen-Van-Tam JS, English A, Falla TJ, et al. Dynamics of meningococcal long-term carriage among university students and their implications for mass vaccination. J Clin Microbiol. 2000;38:2311–6.PubMedGoogle Scholar
- Balkhy HH, Memish ZA, Almuneef MA, Osoba AO. Neisseria meningitidis W-135 carriage during the Hajj season 2003. Scand J Infect Dis. 2004;36:264–8. DOIPubMedGoogle Scholar
- Fijen CA, Kuijper EJ, Tjia HG, Daha MR, Dankert J. Complement deficiency predisposes for meningitis due to nongroupable meningococci and Neisseria-related bacteria. Clin Infect Dis. 1994;18:780–4.PubMedGoogle Scholar
- Findlow H, Vogel U, Mueller JE, Curry A, Njanpop-Lafourcade BM, Claus H, Three cases of invasive meningococcal disease caused by a capsule null locus strain circulating among healthy carriers in Burkina Faso. J Infect Dis. 2007;195:1071–7. DOIPubMedGoogle Scholar
- Yazdankhah SP, Caugant DA. Neisseria meningitidis: an overview of the carriage state. J Med Microbiol. 2004;53:821–32. DOIPubMedGoogle Scholar
- Riordan T, Cartwright KAV, Andrews N, Stuart J, Burris A, Fox A, Acquisition and carriage of meningococci in marine commando recruits. Epidemiol Infect. 1998;121:495–505. DOIPubMedGoogle Scholar
Page created: June 30, 2010
Page updated: June 30, 2010
Page reviewed: June 30, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.