Volume 14, Number 11—November 2008
Dispatch
Metagenomic Diagnosis of Bacterial Infections
Shota Nakamura, Norihiro Maeda, Ionut Mihai Miron, Myonsun Yoh, Kaori Izutsu, Chidoh Kataoka, Takeshi Honda, Teruo Yasunaga, Takaaki Nakaya, Jun Kawai, Yoshihide Hayashizaki, Toshihiro Horii, and Tetsuya Iida
Table
Frequency distributions of species in fecal samples taken from patient during illness and after recovery, as determined by BLASTN*
| Organism | No. (%) |
|
|---|---|---|
| Illness† | Recovery‡ | |
| Bacteroides vulgatus | 5,944 (50.5) | 4,743 (56.5) |
| Homo sapiens | 2,955 (25.1) | 84 (1.0) |
| Parabacteroides distasonis | 818 (6.9) | 1,283 (15.3) |
| B. thetaiotaomicron | 767 (6.5) | 1,046 (12.5) |
| B. fragilis | 759 (6.4) | 842 (10.0) |
| Uncultured bacterium | 195 (1.7) | 227 (2.7) |
| Campylobacter jejuni | 156 (1.3) | 0 |
| B. ovatus | 48 (0.4) | 63 (0.8) |
| Uncultured Bacteroides spp. | 20 (0.2) | 19 (0.2) |
| B. uniformis | 14 (0.1) | 8 (0.1) |
*BLASTN available from http://blast.ncbi.nlm.nih.gov. Expect-value cutoff 10–40.
†Diarrheic fecal sample collected while patient was ill. Total sequences 96,941; total (100%) BLAST matches 11,777.
‡Nondiarrheic fecal sample collected 3 mo after patient had recovered. Total sequences 106,327; total (100%) BLAST matches 8,397.
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Page updated: July 21, 2010
Page reviewed: July 21, 2010
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