Volume 16, Number 1—January 2010
Research
Norovirus Gastroenteritis Outbreak with a Secretor-independent Susceptibility Pattern, Sweden
Johan Nordgren, Elin Kindberg, Per-Eric Lindgren, Andreas Matussek, and Lennart Svensson
Table 2
Influence of secretor status, FUT2 polymorphism, and histo-blood group antigens on risk for norovirus GI.3 symptomatic infection, Sweden*
| Secretor status | OR (95% CI) | p value |
|---|---|---|
| Secretor, n = 68 | 0.71 (0.23–2.18) | 0.57 |
| Nonsecretor, n = 15 |
1.41 (0.46-4.36) |
0.57 |
| FUT2 428 polymorphism | ||
| G/G (secretor), n = 35 | 0.67 (0.27–1.65) | 0.50 |
| G/A (secretor), n = 33 | 1.20 (0.49–2.95) | 0.82 |
| A/A (nonsecretor), n = 15 |
1.41 (0.46–4.36) |
0.57 |
| Histo-blood group antigens | ||
| Blood type,† n = 68 | ||
| A, n = 32 | 1.56 (0.58–4.16) | 0.46 |
| B, n = 12 | 0.27 (0.05–1.33) | 0.11 |
| O, n = 23 | 1.39 (0.50–3.89) | 0.60 |
| AB, n = 1 | Not applicable‡ | 1.0 |
| Lewis, n = 83 | ||
| Lea+b–, n = 12 | 2.42 (0.70–8.42) | 0.21 |
| Lea-b+, n = 61 | 0.73 (0.27–1.95) | 0.61 |
| Lea–b–, n = 10 | 0.61 (0.15–2.57) | 0.73 |
*FUT, fucosyltransferase; OR, odds ratio; CI, confidence interval.
†Compared between secretors. ABO blood group could only be determined for the 68 secretor-positive persons.
‡No carrier of blood type AB was symptomatically infected with norovirus.
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