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Volume 16, Number 11—November 2010
Research

Effect of Vaccination on Bordetella pertussis Strains, China

Liu Zhang1, Yinghua Xu1, Jianhong Zhao, Teemu Kallonen, Shenghui Cui, Yunqiang Xu, Qiming Hou, Fengxiang Li, Junzhi Wang, Qiushui He, and Shumin ZhangComments to Author 
Author affiliations: National Institute for the Control of Pharmaceutical and Biological Products, Beijing, People’s Republic of China (L. Zhang, Y. Xu, S. Cui, Q. Hou, F. Li, J. Wang, S. Zhang); Hebei Medical University, Shijiazhuang, PRC (J. Zhao); The Second Hospital of Shijiazhuang City, Shijiazhuang (Y. Xu); National Institute for Health and Welfare, Turku, Finland (T. Kallonen, Q. He); University of Turku, Turku (T. Kallonen)

Main Article

Figure 3

Dendrogram analysis of 27 pulsed-field gel electrophoresis profiles of Bordetella pertussis isolates circulating in China during 1953–2005. The unweighted pair group method with arithmetic mean with 1% band tolerance and 1% optimization settings was used as the clustering method. * indicates international reference strains (17,23); † indicates vaccine strains from China. Vaccine strains P3s10 and CS represent BpCHR6, and vaccine strain 18530 represents BpFINR13.

Figure 3. Dendrogram analysis of 27 pulsed-field gel electrophoresis profiles of Bordetella pertussis isolates circulating in China during 1953–2005. The unweighted pair group method with arithmetic mean with 1% band tolerance and 1% optimization settings was used as the clustering method. * indicates international reference strains (17,23); † indicates vaccine strains from China. Vaccine strains P3s10 and CS represent BpCHR6, and vaccine strain 18530 represents BpFINR13.

Main Article

References
  1. Kerr  JR, Matthews  RC. Bordetella pertussis infection: pathogenesis, diagnosis, management, and the role of protective immunity. Eur J Clin Microbiol Infect Dis. 2000;19:77–88. DOIPubMedGoogle Scholar
  2. Galanis  E, King  AS, Varughese  P, Halperin  SA; IMPACT investigators. Changing epidemiology and emerging risk groups for pertussis. CMAJ. 2006;174:451–2. DOIPubMedGoogle Scholar
  3. Mooi  FR, He  Q, van Oirschot  H, Mertsola  J. Variation in the Bordetella pertussis virulence factors pertussis toxin and pertactin in vaccine strains and clinical isolates in Finland. Infect Immun. 1999;67:3133–4.PubMedGoogle Scholar
  4. De Melker  HE, Schellekens  JF, Neppelenbroek  SE, Mooi  FR, Rümke  HC, Conyn-van Spaendonck  MA. Reemergence of pertussis in the highly vaccinated population of the Netherlands: observations on surveillance data. Emerg Infect Dis. 2000;6:348–57. DOIPubMedGoogle Scholar
  5. Caro  V, Njamkepo  E, Van Amersfoorth  SC, Mooi  FR, Advani  A, Hallander  HO, Pulsed-field gel electrophoresis analysis of Bordetella pertussis populations in various European countries with different vaccine policies. Microbes Infect. 2005;7:976–82. DOIPubMedGoogle Scholar
  6. Güriş  D, Strebel  PM, Bardenheier  B, Brennan  M, Tachdjian  R, Finch  E, Changing epidemiology of pertussis in the United States: increasing reported incidence among adolescents and adults, 1990–1996. Clin Infect Dis. 1999;28:1230–7. DOIPubMedGoogle Scholar
  7. Elomaa  A, Advani  A, Donnelly  D, Antila  M, Mertsola  J, Hallander  H, Strain variation among Bordetella pertussis isolates in Finland, where the whole-cell pertussis vaccine has been used for 50 years. J Clin Microbiol. 2005;43:3681–7. DOIPubMedGoogle Scholar
  8. Godfroid  F, Denoël  P, Poolman  J. Are vaccination programs and isolate polymorphism linked to pertussis re-emergence? Expert Rev Vaccines. 2005;4:757–78. DOIPubMedGoogle Scholar
  9. Elomaa  A, Advani  A, Donnelly  D, Antila  M, Mertsola  J, He  Q, Population dynamics of Bordetella pertussis in Finland and Sweden, neighbouring countries with different vaccination histories. Vaccine. 2007;25:918–26. DOIPubMedGoogle Scholar
  10. Zhang  XL, Yang  ZW, Zhou  J, Yu  JJ, Wang  KA. An analysis of current epidemiological characteristics of Bordetella pertussis in China [in Chinese]. Chin J Vac Immun. 2000;6:93–5.
  11. Wang  J, Yang  Y, Li  J, Mertsola  J, Arvilommi  H, Shen  X, Infantile pertussis rediscovered in China. Emerg Infect Dis. 2002;8:859–61.PubMedGoogle Scholar
  12. World Health Organization. Immunization, vaccination and biologicals. Vaccine preventable diseases monitoring system: 2009 global summary [cited 2010 Feb 26]. http://www.who.int/immunization_monitoring/en/globalsummary/countryprofileselect.cfm
  13. Hallander  H, Advani  A, Riffelmann  M, von König  CH, Caro  V, Guiso  N, Bordetella pertussis strains circulating in Europe in 1999 to 2004 as determined by pulsed-field gel electrophoresis. J Clin Microbiol. 2007;45:3257–62. DOIPubMedGoogle Scholar
  14. Kallonen  T, He  Q. Bordetella pertussis strain variation and evolution postvaccination. Expert Rev Vaccines. 2009;8:863–75. DOIPubMedGoogle Scholar
  15. Mooi  FR, van Oirschot  H, Heuvelman  K, van der Heide  HG, Gaastra  W, Willems  RJ. Polymorphism in the Bordetella pertussis virulence factors P.69: pertactin and pertussis toxin in the Netherlands: temporal trends and evidence for vaccine-driven evolution. Infect Immun. 1998;66:670–5.PubMedGoogle Scholar
  16. Fry  NK, Neal  S, Harrison  TG, Miller  E, Matthews  R, George  RC. Genotypic variation in the Bordetella pertussis virulence factors pertactin and pertussis toxin in historical and recent clinical isolates in the United Kingdom. Infect Immun. 2001;69:5520–8. DOIPubMedGoogle Scholar
  17. Mooi  FR, Hallander  H, Wirsing von König  CH, Hoet  B, Guiso  N. Epidemiological typing of Bordetella pertussis isolates: recommendations for a standard methodology. Eur J Clin Microbiol Infect Dis. 2000;19:174–81. DOIPubMedGoogle Scholar
  18. Xu  YH, Xu  YQ, Zhang  SM, Wang  LC, Hou  QM, Lei  DL. Development of fluorescence quantitative PCR for detection of Bordetella pertussis and its application [in Chinese]. J Lab Med. 2008;6:690–4.
  19. Tsang  RS, Lau  AK, Sill  ML, Halperin  SA, Van Caeseele  P, Jamieson  F, Polymorphisms of the fimbria fim3 gene of Bordetella pertussis strains isolated in Canada. J Clin Microbiol. 2004;42:5364–7. DOIPubMedGoogle Scholar
  20. Van Loo  IH, Heuvelman  KJ, King  AJ, Mooi  FR. Multilocus sequence typing of Bordetella pertussis based on surface protein genes. J Clin Microbiol. 2002;40:1994–2001. DOIPubMedGoogle Scholar
  21. Advani  A, Donnelly  D, Hallander  H. Reference system for characterization of Bordetella pertussis pulsed-field gel electrophoresis profiles. J Clin Microbiol. 2004;42:2890–7. DOIPubMedGoogle Scholar
  22. Weber  C, Boursaux-Eude  C, Coralie  G, Caro  V, Guiso  N. Polymorphism of Bordetella pertussis isolates circulating for the last 10 years in France, where a single effective whole-cell vaccine has been used for more than 30 years. J Clin Microbiol. 2001;39:4396–403. DOIPubMedGoogle Scholar
  23. Caro  V, Elomaa  A, Brun  D, Mertsola  J, He  Q, Guiso  N. Bordetella pertussis, Finland and France. Emerg Infect Dis. 2006;12:987–9.PubMedGoogle Scholar
  24. Packard  ER, Parton  R, Coote  JG, Fry  NK. Sequence variation and conservation in virulence-related genes of Bordetella pertussis isolates from the UK. J Med Microbiol. 2004;53:355–65. DOIPubMedGoogle Scholar
  25. Lin  YC, Yao  SM, Yan  JJ, Chen  YY, Hsiao  MJ, Chou  CY, Molecular epidemiology of Bordetella pertussis in Taiwan, 1993–2004: suggests one possible explanation for the outbreak of pertussis in 1997. Microbes Infect. 2006;8:2082–7. DOIPubMedGoogle Scholar
  26. Kodama  A, Kamachi  K, Horiuchi  Y, Konda  T, Arakawa  Y. Antigenic divergence suggested by correlation between antigenic variation and pulsed-field gel electrophoresis profiles of Bordetella pertussis isolates in Japan. J Clin Microbiol. 2004;42:5453–7. DOIPubMedGoogle Scholar
  27. Guiso  N, Boursaux-Eude  C, Weber  C, Hausman  SZ, Sato  H, Iwaki  M, Analysis of Bordetella pertussis isolates collected in Japan before and after introduction of acellular pertussis vaccines. Vaccine. 2001;19:3248–52. DOIPubMedGoogle Scholar
  28. Han  HJ, Kamachi  K, Okada  K, Toyoizumi-Ajisaka  H, Sasaki  Y, Arakawa  Y. Antigenic variation in Bordetella pertussis isolates recovered from adults and children in Japan. Vaccine. 2008;26:1530–4. DOIPubMedGoogle Scholar
  29. Chen  I, Finn  TM, Yanqing  L, Guoming  Q, Rappuoli  R, Pizza  M. A recombinant live attenuated strain of Vibrio cholerae induces immunity against tetanus toxin and Bordetella pertussis tracheal colonization factor. Infect Immun. 1998;66:1648–53.PubMedGoogle Scholar
  30. Van Gent  M, de Greeff  SC, van der Heide  HG, Mooi  FR. An investigation into the cause of the 1983 whooping cough epidemic in the Netherlands. Vaccine. 2009;27:1898–903. DOIPubMedGoogle Scholar
  31. Van Gent  M, Pierard  D, Lauwers  S, van der Heide  HG, King  AJ, Mooi  FR. Characterization of Bordetella pertussis clinical isolates that do not express the tracheal colonization factor. FEMS Immunol Med Microbiol. 2007;51:149–54. DOIPubMedGoogle Scholar
  32. Hallander  HO, Advani  A, Donnelly  D, Gustafsson  L, Carlsson  RM. Shifts of Bordetella pertussis variants in Sweden from 1970 to 2003, during three periods marked by different vaccination programs. J Clin Microbiol. 2005;43:2856–65. DOIPubMedGoogle Scholar
  33. Preston  NW. Essential immunogens in human pertussis: the role of fimbriae. Dev Biol Stand. 1985;61:137–41.PubMedGoogle Scholar
  34. Mooi  FR, van Loo  IH, van Gent  M, He  Q, Bart  MJ, Heuvelman  KJ, Bordetella pertussis strains with increased toxin production associated with pertussis resurgence. Emerg Infect Dis. 2009;15:1206–13. DOIPubMedGoogle Scholar

Main Article

1These authors contributed equally to this article.

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