Volume 16, Number 11—November 2010
Research
Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada
Sonia Toracchio, Annette Foyle, Vojtech Sroller1, Jon A. Reed, Jun Wu, Claudia A. Kozinetz, and Janet S. Butel
Table 3
MCPyV infection and characteristics of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma, Nova Scotia, Canada, 1994–2001*
| Characteristic | No. (%) cases | No. (%) MCPyV positive | No. (%) MCPyV negative |
|---|---|---|---|
| Patient sex | |||
| M | 16 (66.7) | 2 (12.5) | 14 (87.5) |
| F |
8 (33.3) |
3 (37.5) |
5 (62.5) |
| Patient age, y | |||
| <60 | 6 (25.0) | 0 | 6 (100.0) |
| >60 |
18 (75.0) |
5 (27.8) |
13 (72.2) |
| Disease stage† | |||
| I | 9 (40.9) | 1 (11.1) | 8 (88.9) |
| II | 5 (22.7) | 3 (60.0) | 2 (40.0) |
| III | 0 | 0 | 0 |
| IV |
8 (36.4) |
1 (12.5) |
7 (87.5) |
| Patient survival‡ | |||
| Alive in remission | 2 (15.4) | 1 (50.0) | 1 (50.0) |
| Alive with disease | 6 (46.1) | 0 | 6 (100.0) |
| Dead from disease |
5 (38.5) |
1 (20.0) |
4 (80.0) |
| Total | 24 | 5 (20.8) | 19 (79.2) |
*No patients with chronic lymphocytic leukemia/small lymphocytic lymphoma had Merkel cell carcinoma. MCPyV, Merkel cell polyomavirus.
†Stage of disease for 2 MCPyV-negative patients was unknown.
‡Five-year follow-up survival information. Data were available for 13 patients, excluding 10 who had received a diagnosis within the past 5 y and one who was lost to follow-up. Disease refers to original diagnosis of either lymphoma or leukemia.
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