Volume 16, Number 11—November 2010
Research
Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada
Sonia Toracchio, Annette Foyle, Vojtech Sroller1, Jon A. Reed, Jun Wu, Claudia A. Kozinetz, and Janet S. Butel
Table 2
Presence of MCPyV in malignant lymphomas, Nova Scotia, Canada, 1994–2001*
| Pathology | No. samples tested | No. (%) MCPyV positive |
|---|---|---|
| Non-Hodgkin lymphoma | 152 | 10 (6.6) |
| B-cell lymphoma | 133 | 8 (6.0) |
| Burkitt lymphoma/Burkitt cell leukemia | 2 | 0 |
| Chronic lymphocytic leukemia/small lymphocytic lymphoma | 24 | 5 (20.8) |
| Diffuse follicular center lymphoma | 1 | 0 |
| Diffuse large B-cell lymphoma | 52 | 0 |
| Diffuse large B-cell lymphoma/T-cell/histiocyte-rich type | 1 | 0 |
| Extranodal marginal zone B-cell lymphoma | 2 | 0 |
| Follicular lymphoma | 35 | 2 (5.7) |
| Lymphoblastic leukemia/lymphoma | 1 | 0 |
| Lymphoplasmacytic lymphoma | 4 | 0 |
| Mantle cell lymphoma | 7 | 0 |
| Posttransplant lymphoproliferative disorder, polymorphic | 1 | 0 |
| Splenic marginal zone lymphoma | 1 | 0 |
| Unclassified | 2 | 1 (50.0) |
| NK/T-cell lymphoma | 18 | 2 (11.0) |
| Anaplastic large cell lymphoma | 8 | 1 (12.5) |
| Angiocentric T cell lymphoma (nasal type) | 1 | 0 |
| Angioimmunoblastic T-cell lymphoma | 2 | 1 (50.0) |
| Extranodal NK/T-cell lymphoma, nasal type | 2 | 0 |
| Lymphoblastic lymphoma | 4 | 0 |
| Peripheral T-cell lymphoma | 1 | 0 |
| Unclassified |
1 |
0 |
| Hodgkin lymphoma | 44 | 3 (6.8) |
| Classical Hodgkin lymphoma | 41 | 3 (7.3) |
| Mixed cellularity | 10 | 2 (20.0) |
| Nodular sclerosis | 29 | 1 (3.4) |
| Unclassified | 2 | 0 |
| Nodular lymphocyte predominant Hodgkin lymphoma |
3 |
0 |
| All | 196 | 13 (6.6) |
*MCPyV, Merkel cell polyomavirus.
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