Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 16, Number 3—March 2010
Research

Invasive Haemophilus influenzae Disease, Europe, 1996–2006

Shamez LadhaniComments to Author , Mary P.E. Slack, Paul T. Heath, Anne von Gottberg, Manosree Chandra, Mary E. Ramsay, and European Union Invasive Bacterial Infection Surveillance participants1
Author affiliations: Health Protection Agency, London, UK (S. Ladhani, M.P.E. Slack, M. Chandra, M.E. Ramsay); National Institute for Communicable Diseases, Johannesburg, South Africa (A. von Gottberg); St. George’s University of London, London (P.T. Heath)

Main Article

Table 4

Epidemiology, diagnosis, and outcome of invasive non–type b Haemophilus influenzae infections, by serotype and age group, Europe, 1996–2006*

Data Hia, n = 26 Hic, n = 9 Hid, n = 12 Hie, n = 143 Hif, n = 500 Total, N = 690
Diagnosis, no. (%) cases
Bacteremia 5 (19.2) 1 (11.1) 0 44 (30.8) 157 (31.4) 207 (30.0)
Pneumonia 3 (11.5) 3 (33.3) 2 (16.7) 28 (19.6) 91 (18.2) 127 (18.4)
Meningitis 6 (23.1) 2 (22.2) 4 (33.3) 22 (15.4) 86 (17.2) 120 (17.4)
Other 6 (23.1) 0 (0) 1 (8.3) 30 (21.0) 87 (17.4) 124 (18.0)
Unknown 6 (23.1) 3 (33.3) 5 (41.7) 19 (13.3) 79 (15.8) 112 (16.2)
Total 26 (100.0) 9 (100.0) 12 (100.0) 143 (100.0) 500 (100.0) 690 (100.0)
Median age at disease onset, y (IQR)
2.1
(0.8–43.7)
52.0
(1.9–53.3)
36.5
(14.4–47.0)
65.3
(34.0–8.3)
61.0
(12.7–75.2)
60.7
(15.4–75.1)
Incidence/million cases (total no. cases) by age group, y
<5 0.12 (17) 0.02 (3) 0 0.10 (14) 0.78 (106) 1.02 (140)
5–64 0.00 (4) 0.00 (5) 0.01 (10) 0.04 (57) 0.12 (171) 0.17 (247)
>65 0.02 (5) 0.00 (1) 0.01 (2) 0.25 (72) 0.77 (221) 1.04 (301)
All age groups
0.01 (26)
0.00 (9)
0.01 (12)
0.08 (143)
0.26 (500)†
0.36 (690)†
No. cases (%) by age group, y
<5 17 (65.4) 3 (33.3) 0 14 (9.8) 106 (21.2) 140 (20.3)
5–64 4 (15.4) 5 (55.6) 10 (83.3) 57 (39.9) 171 (34.2) 247 (35.8)
>65 5 (19.2) 1 (11.1) 2 (16.7) 72 (50.3) 221 (44.2) 301 (43.6)
All age groups
26 (100.0)
9 (100.0)
12 (100.0)
143 (100.0)
500 (100.0)†
690 (100.0)†
No. (%) deaths by age group, y
<5 3 (17.6) 0 0 3 (2.8) 6 (4.3)
5–64 0 1 (20.0) 0 6 (10.5) 11 (6.4) 18 (7.3)
>65 0 0 0 17 (23.6) 22 (10.0) 39 (13.0)
All age groups 3 (11.5) 1 (11.1) 0 23 (16.1) 36 (7.2)† 63 (9.1)†
Median age at death, y (IQR) 0.50
(0.47–2.3) 55.0‡ 70.0
(63.8–88.9) 72.3
(55.9–83.4) 70.5
(51.7–83.7)

*Hia, H. influenzae type a; Hic, H. influenzae type c; Hid, H. influenzae type d; Hie, H. influenzae type e; Hif, H. influenzae type f; IQR, interquartile range.
†Ages were not known for 2 persons with Hif infection.
‡Only 1 death was caused by this serotype.

Main Article

1European Union Invasive Bacterial Infection Surveillance participants: Peter McIntyre, Lyn Gilbert, Geoff Hogg (Australia); Reinhild Strauss, Sigrid Heuberger (Austria); Germaine Hanquet, Francoise Crokaert (Belgium); Pavla Krizova, Vera Lebedova (Czech Republic); Kåre Mølbak, Jens Jørgen Christensen (Denmark); Kuulo Kutsar, Unna Joks (Estonia); Elja Herva, Tarja Kaijalainen, Maija Leinonen, Petri Ruutu (Finland); Agnes Lepoutre, Henri Dabernat (France); Anette Siedler, Heinz-J. Schmitt (Germany); Marie Theodoridou, Anastasia Pangalis, Georgina Tzanakaki (Greece); Miklos Fuzi, Katalin Krisztalovics (Hungary); Thorolfur Gudnason, Hjordis Hardardottir (Iceland); Mary Cafferkey, Suzanne Cotter, Darina O'Flanagan (Republic of Ireland); Ron Dagan (Israel); Marina Cerquetti, Marta Ciofi degli Atti (Italy); Irina Lucenko (Latvia); Grazina Rimseliene, Snieguole Dauksiene (Lithuania); Pierette Huberty-Krau, Francois Schneider (Luxembourg); Jackie Maistre Melillo (Malta); Sabine de Greeff, Hester de Melker, Lodewijk Spanjaard (Netherlands); Hans Blystad, E. Arne Hoiby, Øistein Løvoll (Norway); Andrzej Zielinski, Waleria Hryniewicz, Anna Skoczynska, Marcin Kadlubowski (Poland); Laurinda Queirós, Paula Lavado (Portugal); Claire Cameron, Barbara Denham, Fiona Johnston (Scotland); Margareta Slacikova, Elena Novakova (Slovak Republic); Alenka Kraigher, Metka Paragi (Slovenia); Jose Campos, Javier Diez-Domingo (Spain); Rose-Marie Carlsson, Birgitta Henriques Normark (Sweden); Hans-Peter Zimmermann (Switzerland).

Page created: December 14, 2010
Page updated: December 14, 2010
Page reviewed: December 14, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external