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Volume 10, Number 11—November 2004
Research

Topographic Changes in SARS Coronavirus–infected Cells during Late Stages of Infection

Mah-Lee Ng*Comments to Author , J.W.M. Lee*, M.L.N. Leong*, A.-E. Ling†, H.-C. Tan‡, and E.E. Ooi‡
Author affiliations: *National University of Singapore, Singapore; †Singapore General Hospital, Singapore; ‡National Environment Agency, Singapore

Main Article

Figure 3

Scanning electron microscopy of Vero E6 cells infected with severe acute respiratory syndrome–associated coronavirus at 24 h after infection. A) Cell surface is covered with extracellular progeny virus particles, and progeny virus are being extruded from or attached to numerous pseudopodia on infected cell surface (arrows). B) A higher magnification micrograph of the virus-clustered pseudopodia (arrows). C) Rosettelike appearance of the matured virus particles (arrows). The scanning electron mic

Figure 3. Scanning electron microscopy of Vero E6 cells infected with severe acute respiratory syndrome–associated coronavirus at 24 h after infection. A) Cell surface is covered with extracellular progeny virus particles, and progeny virus are being extruded from or attached to numerous pseudopodia on infected cell surface (arrows). B) A higher magnification micrograph of the virus-clustered pseudopodia (arrows). C) Rosettelike appearance of the matured virus particles (arrows). The scanning electron microscopy image complements the form and structure of the virus seen with negative staining (inset) under transmission electron microscopy. Short and stubby spikes are visible on the virus surface.

Main Article

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Page updated: April 21, 2011
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