Volume 11, Number 8—August 2005
Dispatch
Cost-Benefit of Stockpiling Drugs for Influenza Pandemic
Table A6
Cost-benefit ratios when applying combinations of model parameters in a sensitivity analysis
Probability of pandemic | Estimates of health-related pandemic outcomes* |
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---|---|---|---|---|---|---|---|---|---|
Minimum |
Base case |
Maximum |
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1/100 y | 1/33 y | 1/10 y | 1/100 y | 1/33 y | 1/10 y | 1/100 y | 1/33 y | 1/10 y | |
Strategy | |||||||||
Therapeutic use | |||||||||
All patients | 0.71–0.79 | 2.13–2.37 | 7.10–7.92 | 0.73–0.87 | 2.18–2.62 | 7.25–8.74 | 0.74–0.96 | 2.23–2.88 | 7.42–9.61 |
Patients at high risk | 0.80–1.21 | 2.40–3.63 | 7.99–12.09 | 0.84–1.50 | 2.51–4.49 | 8.36–14.96 | 0.88–1.74 | 2.63–5.23 | 8.76–17.42 |
Preexposure long-term prophylaxis | |||||||||
Entire population | 0.04–0.11 | 0.13–0.34 | 0.42–1.13 | 0.07–0.19 | 0.21–0.58 | 0.71–1.92 | 0.10–0.28 | 0.30–0.83 | 1.00–2.76 |
Patients at high risk | 0.04–0.10 | 0.11–0.30 | 0.38–1.02 | 0.07–0.18 | 0.20–0.55 | 0.67–1.85 | 0.10–0.28 | 0.30–0.83 | 0.99–2.77 |
Postexposure short-term prophylaxis | 0.18–1.14 | 0.54–3.42 | 1.82–11.40 | 0.30–1.94 | 0.91–5.81 | 3.04–19.37 | 0.43–2.78 | 1.30–8.35 | 4.32–27.83 |