Volume 12, Number 1—January 2006
Vaccines for Pandemic Influenza
|Virus subtype||Year||Location||No. cases (no. deaths)||Clinical features||Notes||Reference(s)|
|H5N1||1997||Hong Kong||18 (6)||Associated with outbreak of highly pathogenic AI in poultry in the region||(5,6)|
|H9N2||1999||Hong Kong||2 (0)||Mild influenzalike illness||(7)|
|H9N2||1999||Guangdong Province, China||5 (0)||Mild influenzalike illness||(8)|
|H9N2||2003||Hong Kong||1 (0)||Mild influenzalike illness||(9)|
|H5N1||2003||Hong Kong||2 (1)||Primary viral pneumonia, lymphopenia, respiratory distress||7-year-old girl died in Fujian Province, China, and H5N1 infection was not confirmed. Her 33-year-old father died from confirmed H5N1 influenza infection in Hong Kong, and her 8-year-old brother recovered from H5N1 infection.||(10)|
|H7N7||2003||Netherlands||89 (1)||Conjunctivitis (78 cases), mild influenzalike symptoms (2 cases) or both (5 cases). In fatal case, pneumonia followed by respiratory distress syndrome||Most cases were in persons involved in handling poultry (86), with 3 family members also affected.||(11)|
|H10N7||2004||Egypt||2 (0)||Fever and cough||Both cases were in infants, who recovered without complications||(12)|
|H5N1||2003–present||Asia (Vietnam, Thailand, Cambodia, Indonesia)||116 (60)*||Fever, respiratory symptoms, lymphopenia, elevated liver enzymes. Severe cases progess to respiratory failure, multiple organ dysfunction, and death.||Human cases concomitant with unprecedented outbreaks of highly pathogenic H5N1 AI in poultry||WHO,* (13–15)|
*WHO, World Health Organization. As of September 29, 2005. Source: http://www.who.int/csr/disease/avian_influenza/country/en
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