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Volume 13, Number 3—March 2007


Clostridium difficile in Retail Ground Meat, Canada

Alexander Rodriguez-Palacios*Comments to Author , Henry R. Staempfli*, Todd Duffield*, and J. Scott Weese*
Author affiliations: *University of Guelph, Guelph, Ontario, Canada;

Main Article

Table 2

Drug resistance characteristics of 12 meat-derived Clostridium difficile isolates determined by E-test on Muller-Hinton agar after 48 h of incubation*

Antimicrobial drugMIC50, μg/mLMIC90, μg/mLRange, μg/mL% Resistant isolates
Vancomycin0.50.750.5 to 1.00
Metronidazole0.380.50.19 to 1.00
Levofloxacin32324 to >32100
Clindamycin16.024.08 to >256100

*Breakpoints used were vancomycin susceptible, <4.0 μg/mL; vancomycin resistant >32.0 μg/mL; metronidazole susceptible, <8.0 μg/mL; metronidazole resistant, >32.0 μg/mL; clindamycin susceptible, <2.0 μg/mL; clindamycin resistant >8.0 μg/mL; levofloxacin susceptible, <2.0 μg/mL; levofloxacin resistant, >8.0 μg/mL.

Main Article