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Volume 13, Number 7—July 2007
Synopsis

Thottapalayam Virus, a Prototype Shrewborne Hantavirus

Jin-Won Song*, Luck Ju Baek*, Connie S. Schmaljohn†, and Richard Yanagihara‡Comments to Author 
Author affiliations: *Korea University College of Medicine, Seoul, South Korea; †US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA; ‡University of Hawaii at Manoa, Honolulu, Hawaii, USA;

Main Article

Table 1

Susceptibility of small laboratory animals of various ages to fatal Thottapalayam virus meningoencephalitis*

Host species Age at injection, d Illness onset, d Mortality
rate, %
Mus musculus 1 7 100
5 7 100
10 6 88
14 6 94
21 8 67
Meriones unguiculatus 1 9 100
5 11 100
11 7 80
16 14 100
Peromyscus maniculatus 4 11 100
Monodelphis domestica 30 – 0

*Animals of various ages were injected intracerebrally with 6,000 PFU of Thottapalayam virus strain VRC-66412 and examined daily for neurologic signs and death.

Main Article

Page created: June 21, 2010
Page updated: June 21, 2010
Page reviewed: June 21, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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