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Volume 14, Number 11—November 2008


Possible New Hepatitis B Virus Genotype, Southeast Asia

Christophe M. Olinger, Prapan Jutavijittum, Judith M. Hübschen, Amnat Yousukh, Bounthome Samountry, Te Thammavong, Kan Toriyama, and Claude P. MullerComments to Author 
Author affiliations: National Public Health Laboratory/Centre de Recherche Public–Santé, Luxembourg (C.M. Olinger, J.M. Hübschen, C.P. Muller); Chiang Mai University, Chiang Mai, Thailand (P. Jutavijittum, A. Yousukh); National University of Lao, Vientiane, Laos (B. Samountry); Lao Red Cross, Vientiane (T. Thammavong); Nagasaki University, Nagasaki, Japan (K. Toriyama);

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Table 2

Characteristics of strains most closely related to different recombinant fragments of genotype I (M04-0469): genotypes and genetic distances

Characteristic nt 400–1400 d nt 1400–3000 d nt 3000–400 d
Most similar genotype G 6.29* C 6.29 A 6.23
2nd most similar genotype A 6.84 B 9.14 C 8.61
Most similar subgenotype NA C3 5.42 A4 5.23
Most similar strain G, AF160501 5.51 C3, X75656 4.1 A3, AM184126 4.5
2nd most similar strain G, AB056513 5.62 C1,AB222715 4.3 A4, AY934764 4.7

*Distances (in %) to genotypes of subgenotypes are average distances, that is, the A-like sequence was in average most similar to subgenotype A4 but the minimal distance observed was to an A3 strain. nt, nucleotide; d, distance; NA, not applicable.

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