Volume 14, Number 11—November 2008
Dispatch
Phylogenetics and Pathogenesis of Early Avian Influenza Viruses (H5N1), Nigeria
Table
Virus isolation titers from chickens inoculated with highly pathogenic influenza A/chicken/Nigeria/228-5/2005 (H5N1) and controls*
Sample |
Virus-positive swabs/swabs tested,
no. (mean titer† as log10 EID50/mL) |
Virus-positive tissues/tissues tested, no. (mean titer† as log10 EID50/g) |
||||||
---|---|---|---|---|---|---|---|---|
Oropharyngeal |
Tracheal |
Heart |
Kidney |
Lung |
Muscle |
Brain |
||
Sham | 0/2 | 0/2 | 0/2 | 0/2 | 0/2 | 0/2 | 0/2 | |
Experimental | ||||||||
1 dpi | 2/2 (2.4) | 1/2 (1.7) | 1/2 (2.9) | 1/2 (4.5) | 1/2 (4.9) | 1/2(3.9) | 1/2 (3.5) | |
2 dpi | 2/2 (6.1) | 2/2 (6.8) | 2/2 (8.7) | 2/2 (7.9) | 2/2 (7.6) | 2/2 (6.8) | 2/2 (5.6) |
*Virus isolated from tissues and swabs sample on 1 and 2 days postinoculation (dpi). EID50, mean embryo infectious doses.
†Limit of detection <101.9 EID50/g of tissue or <100.9 EID50/mL sample.
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