Volume 14, Number 12—December 2008
Research
Influenza Infection in Wild Raccoons
Table 3
Antibody production in raccoons experimentally infected with avian influenza virus (H4N8)*
Raccoon ID | Day postinoculation |
Final subtype† | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | ||
264 | N | N | N | N | N | N | N | N | ||||||||
275 | N | N | N | N | N | N | N | N | ||||||||
256 | N | N | N | N | N | WP | SP | SP | H4N8 | |||||||
253 | N | N | N | N | N | N | N | N | ||||||||
260‡ | N | NS | N | N | N | N | N | N | ||||||||
262‡ | P | P | P | P | P | P | WP | WP | H4N8§ | |||||||
258 | N | N | N | N | N | N | N | N | ||||||||
257 | N | N | N | N | N | N | N | N | ||||||||
259 | N | N | N | N | N | ¶ | – | |||||||||
263 | SP | SP | SP | SP | SP | SP | SP | SP | H4N8§ |
*Antibodies were detected by agar gel immunodiffusion, and final subtyping was determined at the National Veterinary Services Laboratories (Ames, IA, USA). N, negative; WP, weakly positive; SP, strongly positive; NS, not sampled; P, positive.
†H, hemagglutinin; N, neuraminidase.
‡Uninoculated raccoons housed in adjacent cages to infected raccoons.
§These raccoons had preexisting antibodies (262:H10N7, 1:10; 263:H4N6 1:40).
¶Raccoon humanely killed 8 days postinoculation.
1Current affiliation: US Geological Survey National Wildlife Health Center, Madison, Wisconsin, USA.