Volume 14, Number 2—February 2008
Research
Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp.
Vincent Cattoir*†‡, Laurent Poirel*†, Camille Aubert*†, Claude-James Soussy‡, and Patrice Nordmann*†
Table
MICs (mg/L) of quinolones and fluoroquinolones for Aeromonas punctata 37, A. media 42, and Escherichia coli TOP10 harboring natural plasmids p37 and p42*
| Antimicrobial agent | A. punctata 37 | A. media 42 | E. coli TOP10 with plasmids |
E. coli TOP10 | |
|---|---|---|---|---|---|
| p37 | p42 | ||||
| Nalidixic acid | >256 | >256 | 4 | 4 | 1 |
| Norfloxacin | 16 | 64 | 1 | 1 | 0.03 |
| Ofloxacin | 8 | >32 | 0.5 | 0.5 | 0.01 |
| Ciprofloxacin | 4 | >32 | 0.12 | 0.25 | <0.01 |
| Moxifloxacin | 4 | 32 | 0.25 | 0.25 | <0.01 |
| Sparfloxacin | 16 | >32 | 0.25 | 0.25 | <0.01 |
| Enrofloxacin | 4 | >32 | 0.5 | 0.5 | <0.01 |
*Each expressing the plasmid-mediated quinolone determinant QnrS2 from A. punctata 37 and A. media 42, respectively, and E. coli reference strain TOP10.
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