Kimberly D. Meade-White
, Kent D. Barbian, Brent Race, Cynthia Favara, Don Gardner, Lara Taubner, Stephen Porcella, and Richard Race
Figure 6. A) Proteinase K–resistant prion protein (PrPres) pathogenicity profiles in Syrian hamsters inoculated with third-passage PrPres. B) Hematoxylin and eosin (H&E)–stained lesion profiles of Syrian hamsters inoculated with brain homogenate derived from third-passage hamsters. Each point represents the average from 6 different animals scored in the following areas: 1, cerebellum; 2, posterior colliculus; 3, superior colliculus; 4, brain stem; 5, spinal cord; 6, thalamus; 7, hypothalamus; 8, hippocampus; 9, cortex; 10, olfactory bulbs; 11, caudate putamen; 12, septal nucleus; 13, tegmentum. Syrian hamster inoculated with third-passage brain homogenate from the following hamster species: ●, Turkish; ■, Djungarian; ♦, Chinese; ▼, Armenian; ▲, Siberian; □, Syrian. Arrows represent differences in multiple regions indicating increases or decreases in vacuolation or PrPres deposition.