Volume 15, Number 3—March 2009
CME ACTIVITY - Research
Clinical Risk Factors for Severe Clostridium difficile–associated Disease
Timothy J. Henrich
, Douglas Krakower, Asaf Bitton, and Deborah S. Yokoe
, Douglas Krakower, Asaf Bitton, and Deborah S. Yokoe
Table 4
Binary logistic regression model to identify variables independently associated with severe CDAD, 336 patients*
| Variable | OR | 95% CI |
|---|---|---|
| Age >70 y | 3.35† | 1.48–7.57 |
| Female | 0.93 | 0.42–2.03 |
| Antimicrobial-drug use | 1.76 | 0.60–5.21 |
| Malignancy | 0.73 | 0.33–1.65 |
| Immunocompromised | 0.38 | 0.07–1.96 |
| Small bowel obstruction or ileus | 3.06‡ | 1.00–9.39 |
| Abnormal abdominal CT scan | 13.54† | 5.72–32.07 |
| Prior hospitalization | 1.39 | 0.61–3.18 |
| SNF/rehabilitation stay | 1.11 | 0.46–2.68 |
*CDAD, Clostridium difficile–associated disease; OR, odds ratio; CI, confidence interval; CT, computed tomography; SNF, skilled-nursing facility. Constant included in analysis.
†p<0.05.
‡p = 0.05.
Page created: December 07, 2010
Page updated: December 07, 2010
Page reviewed: December 07, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.