Figure 1. 5′ untranslated region (A), capsid protein VP1 (B), and complete genome (C) phylogeny of the virus clades studied. Trees were produced by condensing the full phylogeny shown in Technical Appendix 213) and a related clinical strain (CL-Fnp5). HRV-C includes the new clade described since 2006 (9–14,16). Enterovirus 104 (EV-104) and the related strain CL-1231094 refer to a previously unknown enterovirus clade described in this study. In panel C, HRV-C′ is shown in brackets to indicate its expected location (based on VP1 and 3D sequences). Simian picornavirus 1 (SV2) was used as an outgroup. HEV, human enterovirus. Bootstrap support values <50 are not shown in the trees. New viruses are shown in boldface.