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Volume 15, Number 7—July 2009


Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1

William J. BurmanComments to Author , Erin E. Bliven, Lauren Cowan, Lorna Bozeman, Payam Nahid, Lois Diem, Andrew Vernon, and for the Tuberculosis Trials Consortium
Author affiliations: Denver Public Health, Denver Colorado, USA (W.J. Burman); University of Colorado at Denver Health Sciences Center, Denver (W.J. Burman); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.E. Bliven, L. Cowan, L. Bozeman, L. Diem, A. Vernon); The University of California, San Francisco, California, USA (P. Nahid)

Main Article

Table 4

Association between active disease caused by a Beijing genotype of Mycobacterium tuberculosis and relapse, by race/ethnic background, Tuberculosis Trials Consortium Study 22*

Race/ethnicity Patients with disease that relapsed
odds ratio (95% CI) p value
Infected with a Beijing strain, no. positive/no. tested (%) Not infected with a Beijing strain, no. positive/no. tested (%)
Non-Hispanic white (n = 63) 3/11 (27) 17/52 (33) 0.8 (0.2–3.3) 0.73
Non-Hispanic black (n = 148) 6/22 (27) 15/126 (12) 2.8 (0.9–8.2) 0.06
Hispanic (n = 79) 1/7 (14) 7/72 (9.7) 1.5 (0.2–15) 0.70
Asian–Pacific Islander (n = 50) 4/16 (25) 1/34 (2.9) 11 (1.1–108) 0.04

*The Tuberculosis Trials Consortium Study enrolled patients during 1995–1998. Participants in the case–control study were selected from among 1,004 HIV-infected participants. Participants of Native American race/ethnicity (n = 12) were not included because none were infected with a Beijing strain; 2 Native American participants had disease that relapsed. CI, confidence interval.

Main Article

1This study was presented in part at the 2008 International Conference of the American Thoracic Society, May 16–21, 2008, Toronto, Ontario, Canada.