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Volume 15, Number 9—September 2009


Predicting Phenotype and Emerging Strains among Chlamydia trachomatis Infections

Deborah DeanComments to Author , William J. Bruno, Raymond Wan, João P. Gomes, Stéphanie Devignot, Tigist Mehari, Henry J.C. de Vries, Servaas A. Morré, Garry Myers, Timothy D. Read, and Brian G. Spratt
Author affiliations: Children’s Hospital Oakland Research Institute, Oakland, California, USA (D. Dean, R. Wan, T. Mehari); University of California, San Francisco, California, USA (D. Dean); University of California, Berkeley, California, USA (D. Dean); Los Alamos National Laboratories, Los Alamos, New Mexico, USA (W.J. Bruno); National Institute of Health, Lisbon, Portugal (J.P. Gomes); Institut de Médecine Tropicale du Service de Santé des Armées, Marseille, France (S. Devignot); University of Amsterdam, the Netherlands (H.J.C. de Vries); Vrije Universiteit Medical Center, Amsterdam (S.A. Morré); University of Maryland School of Medicine, Baltimore, Maryland, USA (G. Myers); Emory University, Atlanta, Georgia, USA (T.D. Read); Imperial College, London, UK (B.G. Spratt)

Main Article

Table 2

Characteristics of alleles for each locus

Gene locus No. alleles Length, bp No. polymorphic sites Average pairwise distance Average dS Average dN
glyA 7 522 5 0.003 0.0101 0.0034
mdhC 4 519 3 0.001 0.0112 0.0025
pdhA 7 549 6 0.0003 0.0076 0.0030
yhbG 8 504 21 0.01 0.0670 0.0026
pykF 7 525 7 0.003 0.0105 0.0034
lysS 8 576 9 0.002 0.0093 0.0044
Overall 52 3,714 61 0.003

Main Article