Volume 16, Number 10—October 2010
Research
Oral Fluid Testing during 10 Years of Rubella Elimination, England and Wales
Table 1
Accuracy of World Health Organization–modified clinical case definition for rubella, England and Wales, 1999–2008*
Characteristic |
Sensitivity |
Specificity |
Positive predictive value |
|||||
No. positive/ no. tested |
% (95% CI) |
No. positive/ no. tested |
% (95% CI) |
No. positive/ no. tested |
% (95% CI) |
|||
Age, y | ||||||||
<1 | 22/37 | 59.5 (43.6–75.3) | 1,467/2,804 | 52.3 (50.5–54.2) | 22/1,359 | 1.6 (1.0–2.3) | ||
1–4 | 34/75 | 45.3 (34.1–56.6) | 2,303/4,522 | 50.9 (49.5–52.4) | 34/2,253 | 1.5 (1.0–2.0) | ||
5–9 | 7/11 | 63.6 (35.2–92.1) | 1,006/1,640 | 61.3 (59.0–63.7) | 7/641 | 1.1 (0.3–1.9) | ||
10–14 | 10/32 | 31.3 (15.2–47.3) | 298/426 | 70.0 (65.6–74.3) | 10/138 | 7.2 (2.9–11.6) | ||
15–24 | 433/871 | 49.7 (46.4–53.0) | 281/462 | 60.8 (56.4–65.3) | 433/614 | 70.5 (66.9–74.1) | ||
>25 |
256/455 |
56.3 (51.7–60.8) |
257/439 |
58.5 (53.9–63.2) |
256/438 |
58.4 (53.8–63.1) |
||
Sex | ||||||||
M | 649/1,278 | 50.8 (48.0–53.5) | 2,877/5,326 | 54.0 (52.7–55.4) | 649/3,098 | 20.9 (19.5–22.4) | ||
F |
112/202 |
55.4 (48.6–62.3) |
2,744/4,954 |
55.3 (54.0–56.8) |
112/2,322 |
4.8 (3.95–5.7) |
||
Year of report | ||||||||
1995 Jan–1998 Dec | 743/1,435 | 51.8 (49.2–54.4) | 3,630/6,677 | 54.4 (53.2–55.6) | 743/3,790 | 19.6 (18.3–20.9) | ||
1999 Jan–2003 Jul | 18/46 | 39.1 (25.0–53.2) | 1,983/3,616 | 54.8 (53.2–56.5) | 18/1,651 | 1.1 (0.6–1.6) |
*CI, confidence interval.
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