Volume 16, Number 11—November 2010
Dispatch
Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus
Table 1
Genotype | HA | NA | |||||
---|---|---|---|---|---|---|---|
No. sequences | πS ± SE | πN ± SE | No. sequences | πS ± SE | πN ± SE | ||
Pandemic H1N1 (2009) | 397 | 0.0041 ± 0.0015 | 0.0012 ± 0.0003 | 171 | 0.4626 ± 0.0493† | 0.0616 ± 0.0065† | |
H1N1 (pre-2009) | 105 | 0.0926 ± 0.0063 | 0.0171 ± 0.0017 | 105 | 0.0842 ± 0.0088 | 0.0126 ± 0.0016 | |
H3N2 | 562 | 0.1178 ± 0.0094 | 0.0229 ± 0.0028 | 357 | 0.0871 ± 0.0077 | 0.0213 ± 0.0020 | |
H5N1 | 109 | 0.0918 ± 0.0080 | 0.0189 ± 0.0026 | 116 | 0.1034 ± 0.0082 | 0.0194 ± 0.0027
*HA, hemagglutinin; NA, neuraminidase; πS, synonymous nucleotide diversity; πN, nonsynonymous nucleotide diversity. There was a significant difference (p<0.001) between πS and πN in all cases except HA of pandemic (H1N1) 2009. |
*HA, hemagglutinin; NA, neuraminidase; πS, synonymous nucleotide diversity; πN, nonsynonymous nucleotide diversity. There was a significant difference (p<0.001) between πS and πN in all cases except HA of pandemic (H1N1) 2009.
†Significant difference between πS or πN in NA and corresponding value in HA (z-test; p<0.001).
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