Volume 16, Number 2—February 2010
Dispatch
Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
Table 1
Erythrocyte agglutination by representative human, pandemic, swine, and avian H1 influenza virus isolates
Virus isolate | Subtype | Hemagglutination titer of erythrocytes from indicated species, HAU*† |
|||||
---|---|---|---|---|---|---|---|
Turkey‡ | Guinea pig‡ | Chicken§ | Goose§ | Horse¶ | Swine# | ||
Human isolates | |||||||
A/Brisbane/59/2007 | H1N1 | 64 | 64 | 64 | 64 | <2 | <2 |
A/New Jersey/15/2007 |
H1N1 |
32 |
32 |
16 |
16 |
<2 |
<2 |
Pandemic isolates | |||||||
A/California/04/2009 | H1N1 | 64 | 64 | 4 | 16 | <2 | <2 |
A/Tennessee/1-560/2009 |
H1N1 |
32 |
32 |
<2 |
8 |
<2 |
<2 |
Swine isolates | |||||||
A/swine/North Carolina/007270/2008 | H1N1 | 32 | 64 | 8 | 16 | <2 | <2 |
A/swine/Iowa/003479/2009 |
H1N1 |
64 |
64 |
32 |
32 |
2 |
<2 |
Avian isolates | |||||||
A/mallard/Alberta/66/2007 | H1N4 | 64 | 64 | 32 | 32 | 16 | <2 |
A/mallard/Alberta/496/2008 | H1N4 | 64 | 64 | 32 | 32 | 16 | <2 |
*HAU, hemagglutination units.
†Titers are expressed as the reciprocal of the highest virus dilution that yields complete HA agglutination.
‡Neu5Acα2,6Gal > Neu5Acα2,3Gal.
§Neu5Acα2,6Gal < Neu5Acα2,3Gal.
¶Neu5Gc2,3Gal.
#Neu5Gcα2,6Gal > Neu5Gcα2,3Gal.