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Volume 18, Number 1—January 2012


Molecular Evolution of Respiratory Syncytial Virus Fusion Gene, Canada, 2006–2010

Jesse Papenburg, Julie Carbonneau, Marie-Ève Hamelin, Sandra Isabel, Xavier Bouhy, Najwa Ohoumanne, Pierre Déry, Bosco A. Paes, Jacques Corbeil, Michel G. Bergeron, Gaston De Serres, and Guy BoivinComments to Author 
Author affiliations: McGill University Health Centre, Montréal, Québec, Canada (J. Papenburg); Centre de Recherche du Centre Hospitalier Universitaire de Québec, Québec City, Québec, Canada (J. Papenburg, J. Carbonneau, M.-È. Hamelin, S. Isabel, X. Bouhy, P. Déry, J. Corbeil, M.G. Bergeron, G. Boivin); Institut National de Santé Publique du Québec, Québec (N. Ohoumanne, G. De Serres); McMaster Children’s Hospital, Hamilton, Ontario, Canada (B.A. Paes)

Main Article

Table 1

Estimated mean nucleotide and amino acid identities of 170 unique respiratory syncytial virus fusion gene sequences*

Sequence Mean nucleotide identity, % ± SD Mean amino acid identity, % ± SD
Overall, n = 170 89.59 ± 8.38 95.99 ± 3.25
RSV-A (within group), n = 105 97.06 ± 1.33 98.85 ± 0.76
RSV-B (within group), n = 65 98.65 ± 0.69 99.48 ± 0.28
RSV-A vs. RSV-B (between groups), n = 170 80.85 ± 0.66 92.64 ± 0.56

*Mean nucleotide and amino acid identities were estimated by calculating pairwise distances in MEGA5 software ( and using the maximum-composite likelihood and Poisson correction models, respectively. RSV, respiratory syncytial virus.

Main Article