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Volume 18, Number 10—October 2012

WU and KI Polyomaviruses in Respiratory Samples from Allogeneic Hematopoietic Cell Transplant Recipients

Jane Kuypers1Comments to Author , Angela P. Campbell1, Katherine A. Guthrie, Nancy L. Wright, Janet A. Englund, Lawrence Corey, and Michael Boeckh
Author affiliations: University of Washington, Seattle, Washington, USA (J. Kuypers, A.P. Campbell, N.L. Wright, J.A. Englund, L. Corey, M. Boeckh); Fred Hutchinson Cancer Research Center, Seattle (J. Kuypers, A.P. Campbell, K.A. Guthrie, J.A. Englund, L. Corey, M. Boeckh); and Seattle Children’s Hospital, Seattle (A.P. Campbell, J.A. Englund)

Main Article

Table 2

Characteristics of 222 HCT recipients tested for KIPyV or WUPyV*

Characteristic No. (%) recipients
All, n = 222 Infected with either virus, n = 62 Not infected, n = 160
Age, y


23 (10) 18 (29) 5 (3)


37 (17) 14 (23) 23 (14)


99 (45) 17 (27) 82 (51)


63 (28) 13 (21) 50 (31)


87 (39) 23 (37) 64 (40)


135 (61) 39 (63) 96 (60)
Underlying disease risk†


142 (64) 40 (65) 102 (64)


80 (36) 22 (35) 58 (36)
Stem cell source

Bone marrow

28 (13) 12 (19) 16 (10)

Peripheral blood

179 (81) 47 (76) 132 (83)

Cord blood

15 (7) 3 (5) 12 (8)
CMV serostatus


56 (25) 17 (27) 39 (24)


81 (36) 22 (35) 59 (37)


16 (7) 4 (6) 12 (8)


69 (31) 19 (31) 50 (31)
Donor match


77 (35) 23 (37) 54 (34)


9 (4) 6 (10) 3 (2)

Unrelated–cord blood

15 (7) 3 (5) 12 (8)


97 (44) 24 (39) 73 (46)


24 (11) 6 (10) 18 (11)
Conditioning regimen


128 (58) 41 (66) 87 (54)


94 (42) 21 (34) 73 (46)
Acute graft-versus-host disease

Grade 0 or 1

78 (35) 30 (48) 48 (30)

Grade 2–4

144 (65) 32 (52) 112 (70)

*HCT, hematopoietic cell transplantation; KIPyV, KI polyomavirus; WUPyV, WU polyomavirus; CMV, cytomegalovirus; D, donor; R, recipient.
†The underlying disease stage of a patient was categorized as low, intermediate, or high risk (29,31).

Main Article

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1These authors contributed equally to this article.

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Page updated: September 13, 2012
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