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Volume 18, Number 11—November 2012
Research

HIV Infection and Geographically Bound Transmission of Drug-Resistant Tuberculosis, Argentina

Viviana RitaccoComments to Author , Beatriz López, Marta Ambroggi, Domingo Palmero, Bernardo Salvadores, Elida Gravina, Eduardo Mazzeo, Susana Imaz, Lucía Barrera, and National TB Laboratory Network
Author affiliations: Instituto Nacional de Enfermedades Infecciosas ANLIS “Dr. Carlos G. Malbrán,” Buenos Aires, Argentina (V. Ritacco, B. López, E. Mazzeo, L. Barrera); Hospital “Dr. F.J. Muñiz,” Buenos Aires (M. Ambroggi, D. Palmero); Programa Provincial de Tuberculosis, Santa Fe, Argentina (B. Salvadores); Hospital Zonal General Agudos “Dr. Diego Paroissien,” La Matanza, Argentina (E. Gravina); and Instituto Nacional de Enfermedades Respiratorias “Dr. Emilio Coni” ANLIS “Dr Carlos G Malbran,” Santa Fe (S. Imaz)

Main Article

Table 3

Putative risk factors for case-patients with newly diagnosed multidrug-resistant TB in 7 major genotype clusters, Argentina 2003–2009

Cluster
(SIT)* Area Total no. case-patients Risk factor, no. (%) case-patients
Previously treated for TB HIV positive HCWs Other hospital exposure† Prison Household
exposure Unknown
M H2 (2) Buenos Aries 228 78 (34.2) 116 (50.9) 21 (9.2) 38 (16.7) 23 (10.1) 29 (12.7) 19 (8.3)
Ra LAM3 (33) Rosario 89 40 (44.9) 28 (31.5) 2 (2.2) 10 (11.2) 17 (19.1) 16 (18.0) 14 (15.7)
Rb Tuscany
(159) Buenos Aries, Rosario 38 11 (28.9) 22 (57.9) 0 (0.0) 1 (2.6) 0 (0.0) 13‡ (34.2) 6 (15.8)
Pr LAM9 (42) Buenos Aries 26 10 (38.5) 10 (38.5) 0 (0.0) 2 (7.7) 15 (57.7) 5 (19.2) 2 (7.7)
At T1 (53) Atlantic Coast 21 9 (42.9) 7 (33.3) 1 (4.8) 3 (14.3) 2 (9.5) 7 (33.3) 2 (9.5)
Ob LAM5 (725) Buenos Aries 18 7 (38.9) 4 (22.2) 0 (0.0) 2 (11.1) 3 (16.7) 5 (27.8) 2 (11.1)
Os LAM5 (93) Salta 18 7 (38.9) 6 (33.3) 0 (0.0) 3 (16.7) 1 (5.6) 9 (50.0) 2 (11.1)

*Sum does not equal total because of patients with more than one risk factor. Buenos Aires includes the city and surroundings. MDR, multidrug-resistant; TB, tuberculosis; SIT, Shared International Spoligo Type according to Brudey et al. (13); HCW, health care workers.
†Previous hospitalization(s) or concomitant condition.
‡Ten of these case-patients shared a single residence with transvestite sex workers.

Main Article

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1Additional members of the National TB Laboratory Network who contributed data are listed at the end of this article.

Page created: October 16, 2012
Page updated: October 16, 2012
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