Volume 18, Number 5—May 2012
Research
Characterization of Virulent West Nile Virus Kunjin Strain, Australia, 2011
Table 2
Binding pattern of monoclonal antibodies to the viral antigens of 3 WNV strains in fixed-cell ELISA, Australia, 2011*
Virus | Monoclonal antibody, by specificity |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pan-flavivirus† |
WNV group |
WNVKUN |
Unglycosylated WNV E protein |
Glycosylated WNV E protein |
MVEV |
|||||||||
4G4, anti-NS1 | 4G2, anti-E | 2B2, anti-E | 3.91D, anti-E | 10A1, anti-E | 5H1, anti-NS5 | 10C6, anti-NS1 | ||||||||
3.101C | 17D7 | |||||||||||||
WNVNSW2011 | + | + | + | + | + | − | − | + | − | |||||
WNVKUN† | + | + | + | + | + | + | + | − | − | |||||
WNVNY99‡ | + | + | + | + | − | − | − | + | − |
*WNV, West Nile virus; KUN, Kunjin; E, envelope; MVEV, Murray Valley encephalitis virus; NS, nonstructural protein; NS, nonstructural protein; NSW, New South Wales; + positive; –, negative; NY, New York.
†Prototype WNVKUN strain MRM-61C.
‡North American WNV strain.
1These authors contributed equally to the major technical aspects of this research.
2These authors served as joint senior authors.