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Volume 18, Number 6—June 2012
Dispatch
Local Transmission of Imported Endemic Syphilis, Canada, 2011
Sergio Fanella
, Kamran Kadkhoda, Michelle Shuel, and Raymond Tsang
, Kamran Kadkhoda, Michelle Shuel, and Raymond Tsang
Table 2
Comparison of nucleotide sequences of tprI and tprC genes detected in clinical specimens from cases of endemic syphilis, Canada, 2011*
| Strain† | tprI gene sequence at nt positions 1740–1766, 5′ → 3′ | GenBank accession no. |
|---|---|---|
| Clinical strain | CTC CGA TGT TCC CTA CAT GGG CAT TGC | JN674562 |
| Bosnia A | CTC CGA TGT TCC CTA CAT GGG CAT TGC | DQ886678 |
| Nichols‡ | TGC TGA CGC TCC TTA CAT GGG TAT TGC | NC_000919 |
| Samoa D | TGC TGA CGC TCC TTA CAT GGG TAT TGC | DQ886680 |
| tprC gene sequence at nt positions 1704–1736, 5′ → 3′ | ||
| Clinical strain | GGT GCT CTC CGA TGT TCC CTA CAT GGG CAT TGC | JN674563 |
| Bosnia A | GGT GCT CTC CGA TGT TCC CTA CAT GGG CAT TGC | DQ886673 |
| Nichols‡ | CGT GCT TGC TGA CGC TCC TTA CAT GGG CAT TGC | NC_000919 |
| Samoa D | GGT GCT CTC CGA TGT TCC CTA CAT GGG TAT TAC | DQ886671 |
*Boldface indicates differences in nucleotide sequences. BsrDI restriction sites are underlined.
†Sequences were obtained from GenBank: Bosnia A (T. pallidum subsp. endemicum), Samoa D (T. pallidum subsp. pertenue) and syphilis control strain Nichols (T. pallidum subsp. pallidum).
‡Sequence also confirmed in this study.
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