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Volume 18, Number 8—August 2012
Dispatch
Klebsiella pneumoniae in Gastrointestinal Tract and Pyogenic Liver Abscess
Chang-Phone Fung
, Yi-Tsung Lin, Jung-Chung Lin, Te-Li Chen, Kuo-Ming Yeh, Feng-Yee Chang, Han-Chuan Chuang, Hau-Shin Wu, Chih-Peng Tseng, and L. Kristopher Siu
, Yi-Tsung Lin, Jung-Chung Lin, Te-Li Chen, Kuo-Ming Yeh, Feng-Yee Chang, Han-Chuan Chuang, Hau-Shin Wu, Chih-Peng Tseng, and L. Kristopher Siu
Table 2
Virulence of serotype K1 Klebsiella pneumoniae isolates and clonal relationship from patients with liver abscess and healthy carriers, January 2009–December 2010, Taiwan*
| Group no.† | Source | Serum resistance | Phagocytosis, %‡ | Mice LD50, CFU |
|---|---|---|---|---|
| 1 | P1 | R | 30.9 | <2.6 × 102 |
| HC-1 | R | 31.0 | 2.3 × 103 | |
| 2 | P2 | R | 24.2 | <2.9 × 102 |
| P8 | R | 18.3 | <1.5 × 102 | |
| HC-2 | R | 8.8 | 3.5 × 102 | |
| 3 | P7 | S | 86.9 | >1.7 × 105 |
| P6 | R | 29.7 | 2.2 × 102 | |
| HC-3 | R | 35.6 | 3.0 × 102 | |
| 4 | P13 | R | 37.6 | 3.5 × 102 |
| P10 | R | 30.7 | <3.8 × 102 | |
| HC-4 | R | 18.8 | <3.0 × 102 | |
| 5 | P11 | R | 20.4 | 2.3 × 103 |
| HC-5 | R | 13.5 | <2.4 × 102 | |
| 6 | P9 | R | 17.8 | 3.4 × 103 |
| HC-6 | R | 31.7 | 1.7 × 103 | |
| 7 | P4 | S | 35.6 | 1.9 × 104 |
| HC-7 | S | 33.1 | 5.2 × 103 |
*All groups were positive for the rmpA and aerobactin genes. LD50, 50% lethal dose; P, patient; R, resistant: HC, health carrier; S, sensitive.
†Isolates with an identical or clonally related pulsed-field gel electrophoresis profile from liver aspirate and feces of healthy carriers.
‡Percentage of K. pneumoniae phagocytosed by neutrophils after 15 min.
- Page created: July 30, 2012
- Page last updated: July 30, 2012
- Page last reviewed: July 30, 2012
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