Volume 18, Number 8—August 2012
Dispatch
Klebsiella pneumoniae in Gastrointestinal Tract and Pyogenic Liver Abscess
Table 2
Virulence of serotype K1 Klebsiella pneumoniae isolates and clonal relationship from patients with liver abscess and healthy carriers, January 2009–December 2010, Taiwan*
Group no.† | Source | Serum resistance | Phagocytosis, %‡ | Mice LD50, CFU |
---|---|---|---|---|
1 | P1 | R | 30.9 | <2.6 × 102 |
HC-1 | R | 31.0 | 2.3 × 103 | |
2 | P2 | R | 24.2 | <2.9 × 102 |
P8 | R | 18.3 | <1.5 × 102 | |
HC-2 | R | 8.8 | 3.5 × 102 | |
3 | P7 | S | 86.9 | >1.7 × 105 |
P6 | R | 29.7 | 2.2 × 102 | |
HC-3 | R | 35.6 | 3.0 × 102 | |
4 | P13 | R | 37.6 | 3.5 × 102 |
P10 | R | 30.7 | <3.8 × 102 | |
HC-4 | R | 18.8 | <3.0 × 102 | |
5 | P11 | R | 20.4 | 2.3 × 103 |
HC-5 | R | 13.5 | <2.4 × 102 | |
6 | P9 | R | 17.8 | 3.4 × 103 |
HC-6 | R | 31.7 | 1.7 × 103 | |
7 | P4 | S | 35.6 | 1.9 × 104 |
HC-7 | S | 33.1 | 5.2 × 103 |
*All groups were positive for the rmpA and aerobactin genes. LD50, 50% lethal dose; P, patient; R, resistant: HC, health carrier; S, sensitive.
†Isolates with an identical or clonally related pulsed-field gel electrophoresis profile from liver aspirate and feces of healthy carriers.
‡Percentage of K. pneumoniae phagocytosed by neutrophils after 15 min.