Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 18, Number 8—August 2012

Dispatch

Severe Human Granulocytic Anaplasmosis Transmitted by Blood Transfusion

Matjaz JerebComments to Author , Blaz Pecaver, Janez Tomazic, Igor Muzlovic, Tatjana Avsic-Zupanc, Tanja Premru-Srsen, Snezna Levicnik-Stezinar, Primoz Karner, and Franc Strle
Author affiliations: University Medical Center Ljubljana, Ljubljana, Slovenia (M. Jereb, B. Pecaver, J. Tomazic, I. Muzlovic, T. Premru-Srsen); Institute of Microbiology and Immunology, Ljubljana (T. Avsic-Zupanc); and Blood Transfusion Center of Slovenia, Ljubljana (S. Levicnik-Stezinar)

Main Article

Table 2

Results of PCR and IFA for IgG against Anaplasma. phagocytophilum for index patient and blood donor, Slovenia, 2010*

Date, 2010 Patient
Donor
PCR IFA Remarks PCR IFA Remarks
May 12† – – 118 d before index donation
Aug 28–29 ND ND Febrile illness
Sep

7†

 + >1,024 Index donation

15

 – – Transfusion

25

 ND ND Onset of febrile illness
Oct

1

 +‡ – Treatment with doxycycline Oct 1–14

4

 + 128

6

 + 512

9

 + ND

10

 – ND

12

 – 512

19

 ND 512

20

 – >1,024 43 d after index donation
Nov 23 ND >1,024 No reports of problems

*Results for IFA are shown in titers. IFA, immunofluorescence assay; ND, not done; –, negative; +, positive.
†Retrospective testing of stored blood specimen.
‡DNA detected in stored bone marrow–biopsy specimen.

Main Article

Page created: July 19, 2012
Page updated: July 19, 2012
Page reviewed: July 19, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external