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Volume 18, Number 8—August 2012
Dispatch

Severe Human Granulocytic Anaplasmosis Transmitted by Blood Transfusion

Matjaz JerebComments to Author , Blaz Pecaver, Janez Tomazic, Igor Muzlovic, Tatjana Avsic-Zupanc, Tanja Premru-Srsen, Snezna Levicnik-Stezinar, Primoz Karner, and Franc Strle
Author affiliations: University Medical Center Ljubljana, Ljubljana, Slovenia (M. Jereb, B. Pecaver, J. Tomazic, I. Muzlovic, T. Premru-Srsen); Institute of Microbiology and Immunology, Ljubljana (T. Avsic-Zupanc); and Blood Transfusion Center of Slovenia, Ljubljana (S. Levicnik-Stezinar)

Main Article

Table 2

Results of PCR and IFA for IgG against Anaplasma. phagocytophilum for index patient and blood donor, Slovenia, 2010*

Date, 2010 Patient
Donor
PCR IFA Remarks PCR IFA Remarks
May 12† – – 118 d before index donation
Aug 28–29 ND ND Febrile illness
Sep

7†

 + >1,024 Index donation

15

 – – Transfusion

25

 ND ND Onset of febrile illness
Oct

1

 +‡ – Treatment with doxycycline Oct 1–14

4

 + 128

6

 + 512

9

 + ND

10

 – ND

12

 – 512

19

 ND 512

20

 – >1,024 43 d after index donation
Nov 23 ND >1,024 No reports of problems

*Results for IFA are shown in titers. IFA, immunofluorescence assay; ND, not done; –, negative; +, positive.
†Retrospective testing of stored blood specimen.
‡DNA detected in stored bone marrow–biopsy specimen.

Main Article

Page created: July 19, 2012
Page updated: July 19, 2012
Page reviewed: July 19, 2012
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