Volume 19, Number 3—March 2013
Research
Effects of Vaccine Program against Pandemic Influenza A(H1N1) Virus, United States, 2009–2010
Table 1
Data used to calculate effects of vaccination program against influenza A(H1N1)pdm09 virus by population subgroup*
Subgroup | Population | % Vaccinated | No. doses recommended for full coverage | % Assumed outcomes |
||
---|---|---|---|---|---|---|
Vaccine effectiveness† | Clinical cases and hospitalizations | Deaths | ||||
6 mo–9 y | 39,429,115 | 1st dose/45, 2nd dose/23 | 2 doses, 4 wks apart | 1st dose/0, 2nd dose/62 | 20.1 | 6.0 |
10–24 y (10–17 all, 18–24 NP) | 59,684,833 | 27 | 1 | 62 | 22.3 | 8.0 |
Pregnant 18–64 y | 5,578,782 | 43 | 1 | 62 | 2.2 | 4.0 |
25–64 y, HR, NP | 33,949,395 | 27 | 1 | 62 | 13.5 | 24.0 |
25–64 y, HCW, non-HR, NP | 17,451,921 | 36 | 1 | 62 | 5.6 | 9.0 |
25–64 y, contact <6 mo, non-HCW, non-HR, NP | 8,933,718 | 23 | 1 | 62 | 2.5 | 6.0 |
25–64 y, non-contact <6 mo, non-HCW, non-HR, NP | 96,235,755 | 16 | 1 | 62 | 24.0 | 30.0 |
>65 y |
37,989,965 |
28 |
1 |
43 |
9.8 |
13.0 |
Total |
299,253,484 |
27 |
1–2 |
NA |
NA |
NA |
References | (14,28,39) | (9,14,28) | (6) | (24,36,40) | (2,19–21) | (2,19–21) |
*NP, not pregnant; HR, high risk; HCW, health care worker; contact, household contacts and caregivers of children <6 months of age; NA, not applicable.
†Data are for effectiveness against clinical cases, hospitalizations, and deaths. For population subgroup 6 mo–9 y, we assumed the vaccine reached effectiveness levels 2 wk after full coverage (12).
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1Current affiliation: Merck & Co., Inc., Lansdale, Pennsylvania, USA.
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