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Volume 19, Number 4—April 2013
CME ACTIVITY - Research

Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–20101

Patricia FerrieriComments to Author , Ruth Lynfield, Roberta Creti, and Aurea E. Flores
Author affiliations: University of Minnesota Medical School, Minneapolis, Minnesota, USA (P. Ferrieri, A.E. Flores); Minnesota Department of Health, St. Paul, Minnesota, USA (R. Lynfield); Istituto Superiore di Sanità, Rome, Italy (R. Creti)

Main Article

Table 3

Patient characteristics of and clinical data for serotype IV GBS isolates from infants with invasive GBS disease, Minnesota, USA, January 2000–December 2010*

Period Disease type† Patient age at diagnosis Patient outcome Culture source Clindamycin susceptibility‡ Isolate protein profile Isolate PFGE profile
2001–2009 Late-onset 98 d Survived Joint fluid S C-α and BPS 37a
Late-onset 30 d Survived Blood S C-α and BPS 37
Late-onset 9 d Died Blood S BPS 37a
Early-onset 1 d Survived Blood S None 40
Late-onset 9 d Survived Blood S BPS 37a
Early-onset 2 d Survived Blood S BPS 37a
Early-onset 1 d Survived Blood S BPS 37a
2010 Early-onset 1 d Survived Blood R C-α 39a
Early-onset Newborn Survived Blood R C-α 39c
Early-onset Newborn Survived Blood R C-α 39a
Early-onset Newborn Survived Blood R C-α 39a
Early-onset Newborn Survived Blood S BPS 37a

*GBS, group B Streptococcus; PFGE, pulsed-field gel electrophoresis; C-α, C-protein α; BPS, group B protective surface protein.
†Early-onset, patient age birth–6 days; late-onset, patient age 7–180 days.
‡S, susceptible, MIC <0.25 μg/mL; R, resistant, MIC >1 μg/mL.

Main Article

1This work was presented in part at the XVIII Lancefield International Symposium on Streptococci and Streptococcal Diseases, September 4–8, 2011, Palermo, Italy.

Page created: March 14, 2013
Page updated: March 14, 2013
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