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Volume 19, Number 9—September 2013
Research

Antigenic and Molecular Characterization of Avian Influenza A(H9N2) Viruses, Bangladesh

Karthik Shanmuganatham, Mohammed M. Feeroz, Lisa Jones-Engel, Gavin J.D. Smith, Mathieu Fourment, David Walker, Laura McClenaghan, S.M. Rabiul Alam, M. Kamrul Hasan, Patrick Seiler, John Franks, Angie Danner, Subrata Barman, Pamela McKenzie, Scott Krauss, Richard J. Webby, and Robert G. WebsterComments to Author 
Author affiliations: St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (K. Shanmuganatham, D. Walker, L. McClenaghan, P. Seiler, J. Franks, A. Danner, S. Barman, P. McKenzie, S. Krauss, R.J. Webby, R.G. Webster); Jahangirnagar University, Dhaka, Bangladesh (M.M. Feeroz, S.M.R. Alam, M.K. Hasan); University of Washington, Seattle, Washington, USA (L. Jones-Engel); Duke-NUS Graduate Medical School, Singapore (G.J.D. Smith, M. Fourment); Duke Global Health Institute, Durham, North Carolina, USA (G.J.D. Smith)

Main Article

Figure 4

Host range and pathogenicity determinants in avian influenza (H9N2) viruses isolated from different poultry species in Bangladesh during 2008–2011. Numbers in parentheses indicate number of viruses containing specific amino acid residues of the 44 virus isolates analyzed. Blue indicates the 11 genes that were assessed; red indicates the residues that are critical for influenza pathogenesis, enhanced replication in mammalian hosts, or those that are identical to residues present in human influenz

Figure 4. . Host range and pathogenicity determinants in avian influenza (H9N2) viruses isolated from different poultry species in Bangladesh during 2008–2011. Numbers in parentheses indicate number of viruses containing specific amino acid residues of the 44 virus isolates analyzed. Blue indicates the 11 genes that were assessed; red indicates the residues that are critical for influenza pathogenesis, enhanced replication in mammalian hosts, or those that are identical to residues present in human influenza viruses; green indicates unique substitutions in the viruses. HA, hemagglutinin; NA, neuraminidase; M, matrix; NS, nonstructural; NP, nucleoprotein; PA and PB, polymerase genes.

Main Article

Page created: August 20, 2013
Page updated: August 20, 2013
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