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Volume 20, Number 12—December 2014
Research

Molecular Evolution of Peste des Petits Ruminants Virus

Murali Muniraju, Muhammad Munir, AravindhBabu R. Parthiban, Ashley Banyard, Jingyue Bao, Zhiliang Wang, Chrisostom Ayebazibwe, Gelagay Ayelet, Mehdi El Harrak, Mana Mahapatra, Geneviève Libeau, Carrie Batten, and Satya ParidaComments to Author 
Author affiliations: The Pirbright Institute, Pirbright, UK (M. Muniraju, M. Munir, M. Mahapatra, C. Batten, S. Parida); National Institute for Animal Biotechnology, Hyderabad, India (A.R. Parthiban, S Parida); Animal Health and Veterinary Laboratories Agency, Weybridge, UK (A.C. Banyard); China Animal Health and Epidemiology Centre, Qingdao, China (J. Bao, Z. Wang); National Animal Disease Diagnostics and Epidemiology Centre, Entebbe, Uganda (C. Ayebazibwe); National Veterinary Institute, Debre Zeit, Ethiopia (G. Ayelet); Société de Productions Pharmaceutiques et Vétérinaires, Rabat, Morocco (M. El Harrak); Le Centre de Cooperation Internationale en Recherche Agronomique pour le Développement, Montpellier (G. Libeau)

Main Article

Figure 1

Mean ratios of nonsynonymous (dN) to synonymous (dS) substitutions per site of concatenated coding regions of peste des petits ruminants virus genome. Proportion of dS substitutions per potential dS site and proportion of dN substitutions per potential dN site were calculated by using the method of Nei and Gojobori (29) and the suite of nucleotide analysis program (www.hiv.lanl.gov). Vertical dashed lines indicate gene junctions with sliding windows of size = 5 codons. dN/dS values ≥ 10 are show

Figure 1. Mean ratios of nonsynonymous (dN) to synonymous (dS) substitutions per site of concatenated coding regions of peste des petits ruminants virus genome. Proportion of dS substitutions per potential dS site and proportion of dN substitutions per potential dN site were calculated by using the method of Nei and Gojobori (29) and the suite of nucleotide analysis program (www.hiv.lanl.gov). Vertical dashed lines indicate gene junctions with sliding windows of size = 5 codons. dN/dS values ≥ 10 are shown as 10. Numbers along baseline indicate coding regions (basepairs) of individual genes. N, nucleoprotein; P, phosphoprotein; M, matrix; F, fusion; H, hemagglutinin; L, large polymerase.

Main Article

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Main Article

1Preliminary results were presented at the 15th International Negative Strand Virus Meeting, June 16–21, 2013, Granada, Spain.

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