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Volume 20, Number 12—December 2014
Research

Molecular Evolution of Peste des Petits Ruminants Virus

Murali Muniraju, Muhammad Munir, AravindhBabu R. Parthiban, Ashley Banyard, Jingyue Bao, Zhiliang Wang, Chrisostom Ayebazibwe, Gelagay Ayelet, Mehdi El Harrak, Mana Mahapatra, Geneviève Libeau, Carrie Batten, and Satya ParidaComments to Author 
Author affiliations: The Pirbright Institute, Pirbright, UK (M. Muniraju, M. Munir, M. Mahapatra, C. Batten, S. Parida); National Institute for Animal Biotechnology, Hyderabad, India (A.R. Parthiban, S Parida); Animal Health and Veterinary Laboratories Agency, Weybridge, UK (A.C. Banyard); China Animal Health and Epidemiology Centre, Qingdao, China (J. Bao, Z. Wang); National Animal Disease Diagnostics and Epidemiology Centre, Entebbe, Uganda (C. Ayebazibwe); National Veterinary Institute, Debre Zeit, Ethiopia (G. Ayelet); Société de Productions Pharmaceutiques et Vétérinaires, Rabat, Morocco (M. El Harrak); Le Centre de Cooperation Internationale en Recherche Agronomique pour le Développement, Montpellier (G. Libeau)

Main Article

Table 3

Nucleotide substitution rates at codon positions of peste des petits ruminants virus genes by BEAST analysis and dN/dS by SLAC*

Gene†
 Total amino acids
 Codon position Mean dN/dS
CP1.mu
 CP2.mu
 CP3.mu
N 526 0.44 0.33 2.23 0.13
P 510 0.81 0.69 1.49 0.45
M 336 0.48 0.15 2.36 0.06
F 547 0.46 0.26 2.29 0.10
H 610 0.57 0.37 2.06 0.19
L 2184 0.42 0.18 2.40 0.08

*BEAST, Bayesian evolutionary analysis sampling trees; dN/dS, nonsynonymous/synonymous substitutions per site; SLAC, single-likelihood ancestor counting; CP, codon position.
†N = nucleoprotein; P, phosphoprotein; M, matrix; F, fusion; H, hemagglutinin; L, large polymerase.

Main Article

1Preliminary results were presented at the 15th International Negative Strand Virus Meeting, June 16–21, 2013, Granada, Spain.

Page created: November 18, 2014
Page updated: November 18, 2014
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