Subtyping Cryptosporidium ubiquitum,a Zoonotic Pathogen Emerging in Humans
Na Li, Lihua Xiao, Keri Alderisio, Kristin Elwin, Elizabeth Cebelinski, Rachel Chalmers, Monica Santin, Ronald Fayer, Martin Kvac, Una Ryan, Bohumil Sak, Michal Stanko, Yaqiong Guo, Lin Wang, Longxian Zhang, Jinzhong Cai, Dawn Roellig, Yaoyu Feng
, and BohumilSakYaqiongGuoJinzhongCai
Author affiliations: East China University of Science and Technology, Shanghai, China (N. Li, Y. Guo, L. Wang, Y. Feng); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N. Li, L. Xiao, Y. Guo, D. Roellig); New York City Department of Environmental Protection, Flushing, New York, USA (K. Alderisio); UK Cryptosporidium Reference Unit, Swansea, UK (K. Elwin, R. Chalmers); Minnesota Department of Health, St. Paul, Minnesota, USA (E. Cebelinski); US Department of Agriculture, Beltsville, Maryland, USA (M. Santin, R. Fayer); Academy of Science of Czech Republic, České Budějovice, Czech Republic (M. Kvac, B. Sak); Murdoch University, Perth, Australia (U. Ryan); Slovak Academy of Sciences, Košice, Slovakia (M. Stanko); Henan Agricultural University, Zhengzhou, China (L. Zhang); Qinghai Academy of Veterinary Medicine and Animal Science, Xining, China (J. Cai)
Main Article
Figure 1
Figure 1. Deduced amino acid sequence of the gp60 gene of Cryptosporidium ubiquitum compared with sequences of Cparvum and Chominisgp60 sequences from Cubiquitum, Cparvum (GenBank accession noAF022929), and Chominis (GenBank accession noACQ82748) were aligned by using ClustalX (www.clustal.org/)Potential N-linked glycosylation sites are indicated in boldface and italic type, and predicted O-linked glycosylation sites are indicated in boldface and underlined typeThe first 19 aa coding for a signal peptide are highlighted in green, and the last 20 aa for a transmembrane domain are highlighted in blueThe signal peptide cleavage site in the N terminal and furin proteolytic cleavage site between gp40 and gp15 of Cparvum and Chominis are highlighted in yellow and red, respectivelyThe furin cleavage site is not present in CubiquitumDashes denote nucleotide deletions.
Main Article
Page created: January 16, 2014
Page updated: January 16, 2014
Page reviewed: January 16, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.