Volume 20, Number 4—April 2014
Research
Novel Betacoronavirus in Dromedaries of the Middle East, 2013
Patrick C.Y. Woo1
, Susanna K.P. Lau1, Ulrich Wernery, Emily Y.M. Wong, Alan K.L. Tsang, Bobby Johnson, Cyril C.Y. Yip, Candy C.Y. Lau, Saritha Sivakumar, Jian-Piao Cai, Rachel Y.Y. Fan, Kwok-Hung Chan, Ringu Mareena, and Kwok-Yung Yuen
, Susanna K.P. Lau1, Ulrich Wernery, Emily Y.M. Wong, Alan K.L. Tsang, Bobby Johnson, Cyril C.Y. Yip, Candy C.Y. Lau, Saritha Sivakumar, Jian-Piao Cai, Rachel Y.Y. Fan, Kwok-Hung Chan, Ringu Mareena, and Kwok-Yung Yuen
Table 3
Putative transcription regulatory sequence of betacoronavirus A1 members*
| ORF | Putative transcription regulatory sequence (distance, in bases, to AUG)�? |
|||||||
|---|---|---|---|---|---|---|---|---|
| DcCoV UAE-HKU23 | BCoV | CRCoV | SACoV | GiCoV | PHEV | HCoV-OC43 | ECoV | |
| 1ab | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) | UCUAAAC (140) |
| NS2 | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (1) | UCUAAAC (7) | UCUAAAA (12) |
| HE | ACUAAAC (9) | ACUAAAC (9) | ACUAAAC (9) | ACUAAAC (9) | ACUAAAC (9) | ACUAAAC (9) | AUUAAAC (9) | UCUAAAC (9) |
| S | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) | UCUAAAC (0) |
| NS5 | GGUGAAC (51) | GGUAGAC (50) | GGUAGAC (51) | GGUAGAC (50) | GGUAGAC (50) | UUAAGCA (32) | UCUAGCA (20/32) | UAUACUUUAUAA (41) |
| E | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) | UCCAAAC (123) |
| M | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) | UCCAAAC (3) |
| N | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAC (7) | UCUAAAU (7) | UCUAAAC (7) |
*ORF, open reading frame; DcCoV, dromedary camel coronavirus; BCoV, bovine CoV; CRCoV, canine respiratory CoV; SACoV, sable antelopeCoV; GiCoV, giraffe CoV; PHEV, porcine hemagglutinating encephalomyelitis virus; HCoV, human CoV; ECoV, equine CoV; NS, nonstructural protein; HE, hemagglutinin esterase; S, spike protein; E, envelope protein; M, membrane protein; N, nucleocapsid protein.�?"�? Boldface indicates bases and distances to AUG that are different from those for DcCoV UAE-HKU23.
1These authors contributed equally to this article.
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