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Volume 20, Number 5—May 2014


Human Papillomavirus Prevalence in Oropharyngeal Cancer before Vaccine Introduction, United States

Martin SteinauComments to Author , Mona Saraiya, Marc T. Goodman, Edward S. Peters, Meg Watson, Jennifer L. Cleveland, Charles F. Lynch, Edward J. Wilkinson, Brenda Y. Hernandez, Glen Copeland, Maria S. Saber, Claudia Hopenhayn, Youjie Huang, Wendy Cozen, Christopher Lyu, Elizabeth R. Unger, and the HPV Typing of Cancers Workgroup
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Steinau, M. Saraiya, M. Watson, J.L. Cleveland, E.R. Unger); Cedars-Sinai Medical Center, Los Angeles, California, USA (M.T. Goodman); Louisiana State University, New Orleans, Louisiana, USA (E.S. Peters); University of Iowa, Iowa City, Iowa, USA (C.F. Lynch); University of Florida, Gainesville, Florida, USA (E.J. Wilkinson); University of Hawaii, Honolulu, Hawaii, USA (B.Y. Hernandez); Michigan Cancer Surveillance Program, Lansing, Michigan, USA (G. Copeland); Los Angeles Cancer Registry, Los Angeles, California, USA (M.S. Saber, W. Cozen); University of Kentucky, Lexington, Kentucky, USA (C. Hopenhayn); Florida Department of Health, Tallahassee, Florida, USA (Y. Huang); Battelle Memorial Institute, Durham, North Carolina, USA (C. Lyu)

Main Article

Table 5

Multivariate analysis for HPV and 18 detection in 557 oropharyngeal squamous cell carcinoma samples, select United States registries, 1995–2005*

Variable OR (95% CI)† p value
Sex 0.009
F Ref
1.70 (1.14–2.55)

Race/ethnicity <0.001
Non-Hispanic Black Ref
Asian/Pacific Islander 8.43 (2.51–28.29)
Hispanic 4.73 (2.02–11.1)
Non-Hispanic White 4.34 (1.17–97.47)

*HPV, human papillomavirus; OR, odds ratio; Ref, reference group.
†Odds ratio adjusted for race and ethnicity; age was not significant.

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1Members of HPV Typing of Cancers Workgroup who contributed to this study are listed at the end of this article.