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Volume 20, Number 8—August 2014

Levofloxacin-Resistant Haemophilus influenzae, Taiwan, 2004–2010

Shu-Chen Kuo, Pei-Chen Chen, Yih-Ru Shiau, Hui-Ying Wang, Jui-Fen Lai, Wen Huang, and Tsai-Ling Yang LauderdaleComments to Author 
Author affiliations: National Health Research Institutes, Zhunan, Taiwan (S.-C. Kuo, P.-C. Chen, Y.-R. Shiau, H.-Y. Wang, J.-F. Lai, I.-W. Huang, T.-L.Y. Lauderdale); National Yang-Ming University School of Medicine, Taipei, Taiwan (S.-C. Kuo); Taipei Veterans General Hospital, Taipei (S.-C. Kuo)

Main Article

Table 3

Amino acid changes in GyrA and ParC quinolone resistance-determining regions of levofloxacin-resistant Haemophilus influenzae isolates, Taiwan, 2004–2010*

Mutation profile no. Change in GyrA

Change in ParC
No. isolates
S84 D88 S84 E88
2 N I 1
3 A Y I 1
4 D Y I 2
5 F I 1
6 F G I 5
7 F G R 1
8 F N I 14
9 F N R 2
10 F Y K 1
11 F Y I K 16
13 L R K 1
14 L G I 23
15 L G I K 1
16 L G R 41
17 L N 2
18 L N I 42
19 L N R 2
20 L Y K 7
21 L Y I 8
22 L Y I K 1
23 V N I 7
24 Y H K 1
25 Y N I 1
26 Y N I K 1

*PCR products were sequenced and sequences aligned by using Vector NTI (Invitrogen, Carlsbad, CA, USA). Amino acid codes: A, alanine; R, arginine; N, asparagine; D, aspartate; E, glutamate; G, glycine; H, histidine; I, isoleucine; L, leucine; K, lysine; F, phenylalanine; S, serine; Y, tyrosine; V, valine. –, no change.

Main Article

Page created: July 18, 2014
Page updated: July 18, 2014
Page reviewed: July 18, 2014
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