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Volume 21, Number 10—October 2015

Research

Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain

Andrea Marzi, Friederike Feldmann, Patrick W. Hanley, Dana Scott, Stephan Günther, and Heinz FeldmannComments to Author 
Author affiliations: National Institutes of Health, Hamilton, Montana, USA (A. Marzi, F. Feldmann, P.W. Hanley, D.P. Scott, H. Feldmann); Bernard-Nocht-Institute for Tropical Medicine, Hamburg, Germany (S. Günther)

Main Article

Figure 1

Clinical parameters for 6 cynomolgus macaques infected with Ebola virus strains Makona or Mayinga. Parameters were measured for each animal on day of examination and time of euthanasia. A) Temperature profiles. B) Virus titer (viremia). TCID50, 50% tissue culture infectious dose. C) Daily clinical scorel. D) Survival curves showing significant difference in time to death between both groups (p = 0.0295, by Mantel-Cox test).

Figure 1. Clinical parameters for 6 cynomolgus macaques infected with Ebola virus strains Makona or Mayinga. Parameters were measured for each animal on day of examination and time of euthanasia. A) Temperature profiles. B) Virus titer (viremia). TCID50, 50% tissue culture infectious dose. C) Daily clinical scorel. D) Survival curves showing significant difference in time to death between both groups (p = 0.0295, by Mantel-Cox test).

Main Article

Page created: September 22, 2015
Page updated: September 22, 2015
Page reviewed: September 22, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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